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  1. Article

    Open Access

    Redefining the ontogeny of hyalocytes as yolk sac-derived tissue-resident macrophages of the vitreous body

    The eye is a highly specialized sensory organ which encompasses the retina as a part of the central nervous system, but also non-neural compartments such as the transparent vitreous body ensuring stability of ...

    Dennis-Dominik Rosmus, Jana Koch, Annika Hausmann in Journal of Neuroinflammation (2024)

  2. No Access

    Article

    Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection

    The interplay between host and pathogen relies heavily on rapid protein synthesis and accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic interface, we combined Click c...

    Joel Selkrig, Nan Li, Annika Hausmann, Matthew S. J. Mangan in Nature Microbiology (2020)

  3. No Access

    Article

    Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice

    The microbiota confers colonization resistance, which blocks Salmonella gut colonization1. As diet affects microbiota composition, we studied whether food composition shifts enhance susceptibility to infection. S...

    Sandra Y. Wotzka, Markus Kreuzer, Lisa Maier, Markus Arnoldini in Nature Microbiology (2019)

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    Article

    Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut

    The emergence of antibiotic-resistant bacteria through mutations or the acquisition of genetic material such as resistance plasmids represents a major public health issue1,2. Persisters are subpopulations of bact...

    Erik Bakkeren, Jana S. Huisman, Stefan A. Fattinger, Annika Hausmann in Nature (2019)