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Article
Open AccessRedefining the ontogeny of hyalocytes as yolk sac-derived tissue-resident macrophages of the vitreous body
The eye is a highly specialized sensory organ which encompasses the retina as a part of the central nervous system, but also non-neural compartments such as the transparent vitreous body ensuring stability of ...
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Article
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection
The interplay between host and pathogen relies heavily on rapid protein synthesis and accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic interface, we combined Click c...
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Article
Escherichia coli limits Salmonella Typhimurium infections after diet shifts and fat-mediated microbiota perturbation in mice
The microbiota confers colonization resistance, which blocks Salmonella gut colonization1. As diet affects microbiota composition, we studied whether food composition shifts enhance susceptibility to infection. S...
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Article
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
The emergence of antibiotic-resistant bacteria through mutations or the acquisition of genetic material such as resistance plasmids represents a major public health issue1,2. Persisters are subpopulations of bact...