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Article
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling
Adherens junctions (AJs) create spatially, chemically and mechanically discrete microdomains at cellular interfaces. Here, using a mechanogenetic platform that generates artificial AJs with controlled protein ...
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Article
Open AccessEthanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells
Obesogenic lipids and the sphingolipid ceramide have been implicated as potential cofactors in alcoholic liver disease (ALD) patients. However, the mechanisms by which these lipids modulate lipid trafficking i...