34 Result(s)
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Anne-Claire Lukaszewicz
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Open AccessImmune profiling of critically ill patients with acute kidney injury during the first week after various types of injuries: the REALAKI study
Acute kidney injury (AKI) is common in hospitalized patients and results in significant morbidity and mortality. The objective of the study was to explore the systemic immune response of intensive care unit pa...
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Open AccessCorrection: Cefiderocol in Difficult-to-Treat Nf-GNB in ICU Settings
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Open AccessMonitoring monocyte HLA-DR expression and CD4 + T lymphocyte count in dexamethasone-treated severe COVID-19 patients
A 10-day dexamethasone regimen has emerged as the internationally adopted standard-of-care for severe COVID-19 patients. However, the immune response triggered by SARS-CoV-2 infection remains a complex and dyn...
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Open AccessUse of Immune Profiling Panel to assess the immune response of septic patients for prediction of worsening as a composite endpoint
Sepsis induces intense, dynamic and heterogeneous host response modulations. Despite improvement of patient management, the risk of mortality and healthcare-associated infections remains high. Treatments to co...
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Open AccessCefiderocol in Difficult-to-Treat Nf-GNB in ICU Settings
The efficacy and safety of cefiderocol in ICU patients with difficult-to-treat resistance (DTR) non-fermenting Gram-negative bacteria (Nf-GNB) are not as well-established. Consequently, we conducted a cohort s...
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Open AccessComparison of mortality and outcomes of four respiratory viruses in the intensive care unit: a multicenter retrospective study
This retrospective study aimed to compare the mortality and burden of respiratory syncytial virus (RSV group), SARS-CoV-2 (COVID-19 group), non-H1N1 (Seasonal influenza group) and H1N1 influenza (H1N1 group) i...
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Open AccessImmature neutrophils and myeloid-derived suppressor cells in sepsis: differences in occurrence kinetics
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Open AccessAssociation of pronounced elevation of NET formation and nucleosome biomarkers with mortality in patients with septic shock
Understanding the mechanisms underlying immune dysregulation in sepsis is a major challenge in develo** more individualized therapy, as early and persistent inflammation, as well as immunosuppression, play a...
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Open AccessIdentification of a sub-group of critically ill patients with high risk of intensive care unit-acquired infections and poor clinical course using a transcriptomic score
The development of stratification tools based on the assessment of circulating mRNA of genes involved in the immune response is constrained by the heterogeneity of septic patients. The aim of this study is to ...
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In situ high fidelity simulation of the pre procedure start timeframe in cerebral thrombectomy
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Open AccessDysregulated expression of amino-acid and glucose transporters on circulating plasma cells in septic shock patients: a preliminary study
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Open AccessA stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score
Although multiple individual immune parameters have been demonstrated to predict the occurrence of secondary infection after critical illness, significant questions remain with regards to the selection, timing...
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Open AccessLack of SARS-CoV-2-specific cellular response in critically ill COVID-19 patients despite apparent effective vaccination
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Open AccessCorrection to: Recombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patients
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Open AccessRecombinant human interleukin-7 reverses T cell exhaustion ex vivo in critically ill COVID-19 patients
Lymphopenia is a hallmark of severe coronavirus disease 19 (COVID-19). Similar alterations have been described in bacterial sepsis and therapeutic strategies targeting T cell function such as recombinant human...
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Open AccessLongitudinal assessment of IFN-I activity and immune profile in critically ill COVID-19 patients with acute respiratory distress syndrome
Since the onset of the pandemic, only few studies focused on longitudinal immune monitoring in critically ill COVID-19 patients with acute respiratory distress syndrome (ARDS) whereas their hospital stay may l...
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Open AccessCan prone positioning be a safe procedure in patients with acute brain injury and moderate-to-severe acute respiratory distress syndrome?
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Open AccessMulticentric experience with interferon gamma therapy in sepsis induced immunosuppression. A case series
The sepsis-induced immunodepression contributes to impaired clinical outcomes of various stress conditions. This syndrome is well documented and characterized by attenuated function of innate and adaptive immu...
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Open AccessHigh plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients
Biomarkers in sepsis for severity, prediction of outcome or reversibility of organ dysfunction are warranted. Measurements of plasma DAMP levels at admission can reflect the severity of cellular damage in sept...
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Open AccessPlatelet activation and aggregation after aneurysmal subarachnoid hemorrhage
Endovascular techniques have proven beneficial in the treatment of aneurysmal subarachnoid hemorrhage (aSAH), but with high risk of arterial clotting, emboli and dissection. Platelet activation and alterations...
