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  1. No Access

    Article

    Oral nutritional supplement prevents weight loss and reduces side effects in patients in advanced lung cancer chemotherapy

    Weight loss in patients with cancer is caused by cancer cachexia and chemotherapy-induced nausea and vomiting. Recent developments in antiemetic drugs have substantially improved nausea and vomiting, but this ...

    Piera Torricelli, Francesco Antonelli, Pasquale Ferorelli, Ilaria Borromeo… in Amino Acids (2020)

  2. Article

    Open Access

    Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomics

    MDCK cells derived from canine kidney are an important experimental model system for investigating epithelial polarity in mammalian cells. Monoclonal antibodies against apical gp114 and basolateral p58 have se...

    Joachim Füllekrug, Anna Shevchenko, Andrej Shevchenko, Kai Simons in BMC Biochemistry (2006)

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    Article

    Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly

    SCF ubiquitin ligases are composed of Skp1, Cdc53, Hrt1 and one member of a large family of substrate receptors known as F-box proteins (FBPs). Here we report the identification, using sequential rounds of epi...

    Jae Hong Seol, Anna Shevchenko, Andrej Shevchenko… in Nature Cell Biology (2001)

  4. No Access

    Article

    A generic protein purification method for protein complex characterization and proteome exploration

    We have developed a generic procedure to purify proteins expressed at their natural level under native conditions using a novel tandem affinity purification (TAP) tag. The TAP tag allows the rapid purification...

    Guillaume Rigaut, Anna Shevchenko, Berthold Rutz, Matthias Wilm… in Nature Biotechnology (1999)