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Article
Open AccessSymptom-based early-stage differentiation between SARS-CoV-2 versus other respiratory tract infections—Upper Silesia pilot study
In the DECODE project, data were collected from 3,114 surveys filled by symptomatic patients RT-qPCR tested for SARS-CoV-2 in a single university centre in March-September 2020. The population demonstrated bal...
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Chapter and Conference Paper
Can an Integrative SNP Approach Substitute Standard Identification in Comprehensive Case/Control Analyses?
This article describes the use of a comprehensive approach for the identification of differentiating gene related blocks of SNPs based on Fisher’s p-value integration with a pooled correlation approximation. T...
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Article
Open AccessComprehensive Analysis of MILE Gene Expression Data Set Advances Discovery of Leukaemia Type and Subtype Biomarkers
Large collections of data in studies on cancer such as leukaemia provoke the necessity of applying tailored analysis algorithms to ensure supreme information extraction. In this work, a custom-fit pipeline is ...
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Chapter and Conference Paper
Deep Data Analysis of a Large Microarray Collection for Leukemia Biomarker Identification
Nowadays, statistical design of experiments allows for planning of complex studies while maintaining control over technical bias. In this study, the equal importance of performing tailored preprocessing, such ...
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Chapter and Conference Paper
Statistical Integration of p-values for Enhancing Discovery of Radiotoxicity Gene Signatures
The aim of this study is to verify the effectiveness of a statistical integrative approach for merging expression data sets on the level of p-values. The data consist of two independent sets of expression leve...