7 Result(s)

Article

Underrepresentation of ethnic minorities in UK COVID-19 trials: comment on a recent systematic review and meta-analysis

Zeynep Ersoy Guller, Frederick Green, Anna L. Goodman in BMC Medicine (2023)

Article

Real-world effectiveness of steroids in severe COVID-19: a retrospective cohort study

Randomised controlled trials have shown that steroids reduce the risk of dying in patients with severe Coronavirus disease 2019 (COVID-19), whilst many real-world studies have failed to replicate this result. ...

Wenjuan Wang, Luke B Snell, Davide Ferrari, Anna L Goodman… in BMC Infectious Diseases (2022)

Article

Protective CD8⁺ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

Induction of antigen-specific CD8⁺ T cells offers the prospect of immunization against many infectious diseases, but no subunit vaccine has induced CD8⁺ T cells that correlate with efficacy in humans. Here we dem...

Katie J. Ewer, Geraldine A. O’Hara, Christopher J. A. Duncan… in Nature Communications (2013)

Article

Correction: Corrigendum: The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

Nature Communications 2: Article number: 601 (2011); Published: 20 December 2011; Updated: 19 September 2013. In the Methods section of this Article, the species of the tissue plasminogen activator secretory s...

Alexander D. Douglas, Andrew R. Williams, Joseph J. Illingworth… in Nature Communications (2013)

Article

The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment

Rodent malaria species Plasmodium yoelii and P. chabaudi have been widely used to validate vaccine approaches targeting blood-stage merozoite antigens. However, increasing data suggest the P. berghei rodent malar...

Anna L. Goodman, Emily K. Forbes, Andrew R. Williams… in Scientific Reports (2013)

Article

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

Current vaccine strategies against the asexual blood stage of Plasmodium falciparum are mostly focused on well-studied merozoite antigens that induce immune responses after natural exposure, but have yet to induc...

Alexander D. Douglas, Andrew R. Williams, Joseph J. Illingworth… in Nature Communications (2011)

Article

Effective induction of high-titer antibodies by viral vector vaccines

A novel immunization strategy that involves prime-boost vaccination with a recombinant adenovirus-poxvirus vector can induce strong, antigen-specific antibody responses. Antibodies induced by this viral-vector...

Simon J Draper, Anne C Moore, Anna L Goodman, Carole A Long… in Nature Medicine (2008)