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Article
Kernel Based Non-Iterative Automatic Fast Capacitance Compensation in Patch-Clamp Experiments
Patch-clamp recording is a widely used technique for studying ion channel functions and cellular responses. During patch-clamp experiments, the fast capacitance (CFast) transient is a detrimental artifact and ...
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Article
Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation
Feeding behaviour is modulated by both environmental cues and internal physiological states. Appetite is commonly boosted by the pleasant smell (or appearance) of food and destroyed by a bad taste. In reality,...
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Chapter and Conference Paper
Labeling GLUT4 with quantum dots for 3D tracking in live L6 cells
Quantum dots (QDs) are light-emitting semiconductor nanoparticles with unique optical and spectroscopic properties, and are emerging as an alternative to conventional dyes for fluorescence-based applications. ...
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Article
Z f-and-H sys-based C m measurement under the whole-cell patch-clamp recording
Membrane capacitance (C m) measurement, which measures and monitors plasma membrane capacitance and its changes of a cell, is one of the most important quantitative techniques and widely u...
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Chapter and Conference Paper
KATP channel is conveyed to plasma membrane by constitutive exocytosis
Adenosine triphosphate (ATP)-sensitive K+ (KATP) channels regulate many cellular functions by coupling the metabolic state of the cell to the changes in membrane potential. Truncation of C-terminal 26 amino acid ...
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Article
Ca2+ signals induced from calcium stores in pancreatic islet β cells
In single rat pancreatic β cells, using fura-2 microfluorometry to measure [Ca2+]i response upon different stimuli, the ways of calcium regulation have been studied. When the extracellular calcium concentration w...
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Article
Mechanisms of peroxynitrite-induced [Ca2+]i increase in single neuronal cell
The mechanism of peroxynitrite (ONOO−)-induced [ca2+]i increase in single MN9D cell (Dopaminergic neuroblastoma cell line) was studied by using Fura-2 microfluorometric technique. The results show that ONOO− caus...