71 Result(s)

Article

The determinants of change in tibial plateau bone area in osteoarthritic knees: a cohort study

Bone is integral to the pathogenesis of osteoarthritis (OA). Whether the bone area of the tibial plateau changes over time in subjects with knee OA is unknown. We performed a cohort study to describe this and ...

Yuanyuan Wang, Anita E Wluka, Flavia M Cicuttini in Arthritis Research & Therapy (2005)

Article

Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years

The objective of this study was to describe the rate of change in knee cartilage volume over 4.5 years in subjects with symptomatic knee osteoarthritis (OA) and to determine factors associated with cartilage l...

Anita E Wluka, Andrew Forbes, Yuanyuan Wang, Fahad Hanna… in Arthritis Research & Therapy (2006)

Article

Effect of antioxidants on knee cartilage and bone in healthy, middle-aged subjects: a cross-sectional study

The aim of the present study is to examine the effect of dietary antioxidants on knee structure in a cohort of healthy, middle-aged subjects with no clinical knee osteoarthritis.

Yuanyuan Wang, Allison M Hodge, Anita E Wluka… in Arthritis Research & Therapy (2007)

Article

Factors that may mediate the relationship between physical activity and the risk for develo** knee osteoarthritis

Studies investigating the effect of physical activity on risk for develo** osteoarthritis at weight-bearing joints have reported conflicting results. We examine evidence to suggest that this may be due to th...

Donna M Urquhart, Cathy Soufan, Andrew J Teichtahl… in Arthritis Research & Therapy (2008)

Article

What is the clinical and ethical importance of incidental abnormalities found by knee MRI?

Magnetic resonance imaging (MRI) is increasingly used to examine joints for research purposes. It may detect both suspected and unsuspected abnormalities. This raises both clinical and ethical issues, especial...

Rebecca Grainger, Stephen Stuckey, Richard O'Sullivan… in Arthritis Research & Therapy (2008)

Article

High sensitivity C-reactive protein is associated with lower tibial cartilage volume but not lower patella cartilage volume in healthy women at mid-life

Elevated serum high sensitivity C-reactive protein (hsCRP) has been reported in established osteoarthritis (OA). The aim of this study was to determine whether serum levels of hsCRP are associated with the var...

Fahad S Hanna, Robin J Bell, Flavia M Cicuttini… in Arthritis Research & Therapy (2008)

Article

Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study

Meniscal injury is a risk factor for the development and progression of knee osteoarthritis, yet little is known about risk factors for meniscal pathology. Joint loading mediated via gait parameters may be ass...

Miranda L Davies-Tuck, Anita E Wluka, Andrew J Teichtahl… in Arthritis Research & Therapy (2008)

Article

Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population

Although vastus medialis and lateralis are important determinants of patellofemoral joint function, their relationship with patellofemoral joint structure is unknown. The aim of this study was to examine poten...

Patricia A Berry, Andrew J Teichtahl… in Arthritis Research & Therapy (2008)

Article

Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study

Total joint replacement is considered a surrogate measure for symptomatic end-stage osteoarthritis. It is unknown whether the adipose mass and the distribution of adipose mass are associated with the risk of p...

Yuanyuan Wang, Julie Anne Simpson, Anita E Wluka… in Arthritis Research & Therapy (2009)

Article

Dietary fatty acid intake affects the risk of develo** bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study

Fatty acids have been implicated in osteoarthritis (OA), yet the mechanism by which fatty acids affect knee structure and consequently the risk of knee OA has not been fully elucidated. Higher intakes of fatty...

Yuanyuan Wang, Miranda L Davies-Tuck, Anita E Wluka… in Arthritis Research & Therapy (2009)

Article

Reduced rates of primary joint replacement for osteoarthritis in Italian and Greek migrants to Australia: the Melbourne Collaborative Cohort Study

Racial and ethnic disparities in rates of total joint replacement have been described, but little work has been done in well-established migrant groups. The aim of this study was to compare the rates of primar...

Yuanyuan Wang, Julie A Simpson, Anita E Wluka… in Arthritis Research & Therapy (2009)

Article

Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study

Given the emerging evidence that osteoarthritis (OA) may have a vascular basis, the aim of this study was to determine whether serum lipids were associated with change in knee cartilage, presence of bone marro...

Miranda L Davies-Tuck, Fahad Hanna, Susan R Davis… in Arthritis Research & Therapy (2009)

Article

Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study

To examine the relationship between development or resolution of bone marrow lesions (BMLs) and knee cartilage properties in a 2 year prospective study of asymptomatic middle-aged adults.

Miranda L Davies-Tuck, Anita E Wluka, Andrew Forbes… in Arthritis Research & Therapy (2010)

Article

The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

To examine the natural history of subchondral bone cysts and to determine whether knee cartilage loss and risk of joint replacement is higher in knees with cysts, compared with those with bone marrow lesions (...

Stephanie K Tanamas, Anita E Wluka, Jean-Pierre Pelletier… in Arthritis Research & Therapy (2010)

Article

The associations between indices of patellofemoral geometry and knee pain and patella cartilage volume: a cross-sectional study

Whilst patellofemoral pain is one of the most common musculoskeletal disorders presenting to orthopaedic clinics, sports clinics, and general practices, factors contributing to its development in the absence o...

Stephanie K Tanamas, Andrew J Teichtahl, Anita E Wluka… in BMC Musculoskeletal Disorders (2010)

Article

Does an increase in body mass index over 10 years affect knee structure in a population-based cohort study of adult women?

Although obesity is a modifiable risk factor for knee osteoarthritis (OA), the effect of weight gain on knee structure in young and healthy adults has not been examined. The aim of this study was to examine th...

Sharon L Brennan, Flavia M Cicuttini, Julie A Pasco… in Arthritis Research & Therapy (2010)

Article

Meat consumption and risk of primary hip and knee joint replacement due to osteoarthritis: a prospective cohort study

There is emerging evidence for a beneficial effect of meat consumption on the musculoskeletal system. However, whether it affects the risk of knee and hip osteoarthritis is unknown. We performed a prospective ...

Yuanyuan Wang, Julie Anne Simpson, Anita E Wluka… in BMC Musculoskeletal Disorders (2011)

Article

Fat mass is associated with disabling foot pain

Stephanie K Tanamas, Anita E Wluka, Patricia Berry… in Journal of Foot and Ankle Research (2011)

Article

Effects of Hylan G-F 20 supplementation on cartilage preservation detected by magnetic resonance imaging in osteoarthritis of the knee: a two-year single-blind clinical trial

Although viscosupplementation is an effective symptomatic treatment for knee osteoarthritis (OA), the effect of longer term administration on articular cartilage has not been fully explored. We examined the ef...

Yuanyuan Wang, Stephen Hall, Fahad Hanna, Anita E Wluka… in BMC Musculoskeletal Disorders (2011)

Article

The associations between body and knee height measurements and knee joint structure in an asymptomatic cohort

It has been suggested that knee height is a determinant of knee joint load. Nonetheless, no study has directly examined the relationship between anthropometric measures of height and knee joint structures, suc...

Andrew J Teichtahl, Anita E Wluka, Boyd J Strauss… in BMC Musculoskeletal Disorders (2012)