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Article
Open AccessImpaired metal perception and regulation of associated human foliate papillae tongue transcriptome in long-COVID-19
Chemosensory impairment is an outstanding symptom of SARS-CoV-2 infections. We hypothesized that measured sensory impairments are accompanied by transcriptomic changes in the foliate papillae area of the tongu...
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Article
Open AccessAssessing the extent and timing of chemosensory impairments during COVID-19 pandemic
Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented med...
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Article
Open AccessIntegrated microbiota and metabolite profiles link Crohn’s disease to sulfur metabolism
Gut microbial and metabolite alterations have been linked to the pathogenesis of inflammatory bowel diseases. Here we perform a multi-omics microbiome and metabolite analysis of a longitudinal cohort of Crohn’...
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Article
Model studies on benzene formation from benzaldehyde
The carcinogenic aromatic hydrocarbon benzene has recently been detected in drinks with added cherry flavour, and it was suggested that benzene could be formed from benzaldehyde used as flavouring. To get a de...
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Article
Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal
Regulatory myeloid immune cells, such as myeloid-derived suppressor cells (MDSCs), populate inflamed or cancerous tissue and block immune cell effector functions. The lack of mechanistic insight into MDSC supp...
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Article
Mass-spectrometry-based draft of the Arabidopsis proteome
Plants are essential for life and are extremely diverse organisms with unique molecular capabilities1. Here we present a quantitative atlas of the transcriptomes, proteomes and phosphoproteomes of 30 tissues of t...
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Chapter
Vision des Software Herstellers OPTIMAL SYSTEMS
Die Zukunft liegt in den Cloud-Technologien. Die Aufwände für die Administration der Infrastruktur werden dann nicht mehr durch die Kunden geleistet, sondern als Service abgerufen. Dann kommen auch kleinere Ve...
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Article
Open AccessThe gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism
As the gut microbiota contributes to metabolic health, it is important to determine specific diet-microbiota interactions that influence host metabolism. Bile acids and dietary fat source can alter phenotypes ...
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Article
Bioappearance and pharmacokinetics of bioactives upon coffee consumption
Habitual consumption of medium amounts of coffee over the whole life-span is hypothesized to reduce the risk to develop diabetes type 2 (DM2) and Alzheimer’s disease (AD). To identify putative bioactive coffee...
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Article
A Role of the Epithelial Sodium Channel in Human Salt Taste Transduction?
Mammals perceive the five different taste qualities: bitter, sweet, umami, sour, and salty. At least two different mechanisms contribute to salt taste in rodents. One is elicited by various cations and sensiti...
