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Clinical High Risk for Psychosis (CHR-P) in children and adolescents: a roadmap to strengthen clinical utility through conceptual clarity
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Open AccessRunning in the FAMILY: understanding and predicting the intergenerational transmission of mental illness
Over 50% of children with a parent with severe mental illness will develop mental illness by early adulthood. However, intergenerational transmission of risk for mental illness in one’s children is insufficien...
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From economic crisis and climate change through COVID-19 pandemic to Ukraine war: a cumulative hit-wave on adolescent future thinking and mental well-being
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Open AccessThe temporal dynamics of transition to psychosis in individuals at clinical high-risk (CHR-P) shows negative prognostic effects of baseline antipsychotic exposure: a meta-analysis
Meta-analytic evidence indicates that baseline exposure to antipsychotics (AP) in individuals at clinical high-risk for psychosis (CHR-P) is associated with an even higher risk of transition to psychosis. Howe...
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Living Reference Work Entry In depth
Alterations of Speech, Thought, Perception, and Self-Experience
This chapter presents and discusses alterations in several domains of human mental activity (speech, thought, perception, and self-experience) which may contribute to the overall sha** of the clinical pictur...
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Open AccessAntipsychotic prescription, assumption and conversion to psychosis: resolving missing clinical links to optimize prevention through precision
The current concept of clinical high-risk(CHR) of psychosis relies heavily on “below-threshold” (i.e. attenuated or limited and intermittent) psychotic positive phenomena as predictors of the risk for future p...
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Open AccessEarly intervention in psychiatry through a developmental perspective
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Subjective experience of social cognition in adolescents at ultra-high risk of psychosis: findings from a 24-month follow-up study
Deficits in social cognition have been reported in people at ultra-high risk (UHR) of psychosis exclusively using socio-cognitive tasks and in adolescent and young adult mixed population. Aim of this study was...
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Open AccessHow to improve adherence to antidepressant treatments in patients with major depression: a psychoeducational consensus checklist
Studies conducted in primary care as well as in psychiatric settings show that more than half of patients suffering from major depressive disorder (MDD) have poor adherence to antidepressants. Patients prematu...
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Anhedonia in adolescents at ultra-high risk (UHR) of psychosis: findings from a 1-year longitudinal study
Previous findings suggested deficits in pleasure experience in schizophrenia, but little is known in psychosis risk prodrome, especially in adolescence. Aim of this study was (1) to assess anhedonia in distinc...
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Parents’ Personality-Disorder Symptoms Predict Children’s Symptoms of Anxiety and Depressive Disorders – a Prospective Cohort Study
Personality disorder (PD) symptomatology is characterized by interpersonal problems and emotional dysregulation, which may affect offspring of parents with PD symptoms. Notably though, studies are needed to di...
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Factor mixture analysis of paranoia in young people
Paranoid thoughts are relatively common in the general population and can increase the risk of develo** mental health conditions. In this study, we investigate the latent structure of paranoia in a sample of...
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Adolescents at ultra-high risk of psychosis in Italian neuropsychiatry services: prevalence, psychopathology and transition rate
Studies in adolescents on ultra-high risk (UHR) and basic symptoms (BS) criteria for psychosis prediction are scarce. In Italy, early interventions in psychosis are less widespread than in other European count...
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Hallucinatory Symptomatology in Major Psychoses (Schizophrenia and Bipolar Disorders)
Albeit endowed with clinical and semeiologic commonalities and often addressed as a broad index of severity and poor prognostic outcome in severe mental disorders, productive symptoms (i.e., delusions, halluci...
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From Thoughts to Voices: Understanding the Development of Auditory Hallucinations in Schizophrenia
Drawing upon core phenomenological contributions of the last decades, the present paper provides an integrated description of the development of auditory hallucinations in schizophrenia. Specifically, these co...
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First- and second-generation antipsychotic drug treatment and subcortical brain morphology in schizophrenia
Antipsychotic medication may influence brain structure, but to what extent effects of first-generation antipsychotics (FGAs) and second-generation antipsychotics (SGAs) differ is still not clear. Here we aime...
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Shades of vulnerability: latent structures of clinical caseness in prodromal and early phases of schizophrenia
The underlying structures of clinical caseness and need of care in prodromal (i.e., at-risk) and early phases of schizophrenia remain poorly characterized in their essential psycho-behavioral coherence. To ide...
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Auditory verbal hallucinations: Dialoguing between the cognitive sciences and phenomenology
Auditory verbal hallucinations (AVHs) are a highly complex and rich phenomena, and this has a number of important clinical, theoretical and methodological implications. However, until recently, this fact has n...
