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  1. Article

    Open Access

    How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?

    Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, “Biology in Space and Analogue...

    Craig R. G. Willis, Marco Calvaruso, Debora Angeloni, Sarah Baatout in npj Microgravity (2024)

  2. Article

    Open Access

    How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

    Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gr...

    Trent Davis, Kevin Tabury, Shouan Zhu, Debora Angeloni, Sarah Baatout in npj Microgravity (2024)

  3. Article

    Open Access

    How do gravity alterations affect animal and human systems at a cellular/tissue level?

    The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gra...

    Francesca Cialdai, Austin M. Brown, Cory W. Baumann, Debora Angeloni in npj Microgravity (2023)

  4. Article

    Open Access

    Ultra-rare RTEL1 gene variants associate with acute severity of COVID-19 and evolution to pulmonary fibrosis as a specific long COVID disorder

    Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused an ongoing pandemic of a pathology termed Coronavirus Disease 19 (COVID-19). Several studies reported that both C...

    Laura Bergantini, Margherita Baldassarri, Miriana d’Alessandro in Respiratory Research (2023)

  5. Article

    Open Access

    A protein-coated micro-sucker patch inspired by octopus for adhesion in wet conditions

    In medical robotics, micromanipulation becomes particularly challenging in the presence of blood and secretions. Nature offers many examples of adhesion strategies, which can be divided into two macro-categori...

    Gabriella Meloni, Omar Tricinci, Andrea Degl’Innocenti in Scientific Reports (2020)

  6. Article

    Open Access

    A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers

    In most mammals, a vast array of genes coding for chemosensory receptors mediates olfaction. Odorant receptor (OR) genes generally constitute the largest multifamily (> 1100 intact members in the mouse). From ...

    Andrea Degl’Innocenti, Gabriella Meloni, Barbara Mazzolai in BMC Bioinformatics (2019)

  7. Article

    Open Access

    Three-dimensional reconstruction of root shape in the moth orchid Phalaenopsis sp.: a biomimicry methodology for robotic applications

    Within the field of biorobotics, an emerging branch is plant-inspired robotics. Some effort exists in particular towards the production of digging robots that mimic roots; for these, a deeper comprehension of ...

    Anand Kumar Mishra, Andrea Degl’Innocenti, Barbara Mazzolai in BMC Research Notes (2018)

  8. Article

    Open Access

    Ultrasound-Activated Piezoelectric Nanoparticles Inhibit Proliferation of Breast Cancer Cells

    A nanotechnology-based approach for the inhibition of breast cancer cell proliferation is proposed. The innovative solution consists in a platform based on biocompatible piezoelectric nanoparticles able to tar...

    Attilio Marino, Matteo Battaglini, Daniele De Pasquale in Scientific Reports (2018)

  9. Article

    Open Access

    Chlorophyll derivatives enhance invertebrate red-light and ultraviolet phototaxis

    Chlorophyll derivatives are known to enhance vision in vertebrates. They are thought to bind visual pigments (i.e., opsins apoproteins bound to retinal chromophores) directly within the retina. Consistent with pr...

    Andrea Degl’Innocenti, Leonardo Rossi, Alessandra Salvetti in Scientific Reports (2017)