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Open AccessHow to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?
Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, “Biology in Space and Analogue...
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Article
Open AccessHow are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?
Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gr...
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Article
Open AccessHow do gravity alterations affect animal and human systems at a cellular/tissue level?
The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gra...
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Open AccessUltra-rare RTEL1 gene variants associate with acute severity of COVID-19 and evolution to pulmonary fibrosis as a specific long COVID disorder
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused an ongoing pandemic of a pathology termed Coronavirus Disease 19 (COVID-19). Several studies reported that both C...
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Open AccessA protein-coated micro-sucker patch inspired by octopus for adhesion in wet conditions
In medical robotics, micromanipulation becomes particularly challenging in the presence of blood and secretions. Nature offers many examples of adhesion strategies, which can be divided into two macro-categori...
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Open AccessA purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers
In most mammals, a vast array of genes coding for chemosensory receptors mediates olfaction. Odorant receptor (OR) genes generally constitute the largest multifamily (> 1100 intact members in the mouse). From ...
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Open AccessThree-dimensional reconstruction of root shape in the moth orchid Phalaenopsis sp.: a biomimicry methodology for robotic applications
Within the field of biorobotics, an emerging branch is plant-inspired robotics. Some effort exists in particular towards the production of digging robots that mimic roots; for these, a deeper comprehension of ...
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Open AccessUltrasound-Activated Piezoelectric Nanoparticles Inhibit Proliferation of Breast Cancer Cells
A nanotechnology-based approach for the inhibition of breast cancer cell proliferation is proposed. The innovative solution consists in a platform based on biocompatible piezoelectric nanoparticles able to tar...
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Open AccessChlorophyll derivatives enhance invertebrate red-light and ultraviolet phototaxis
Chlorophyll derivatives are known to enhance vision in vertebrates. They are thought to bind visual pigments (i.e., opsins apoproteins bound to retinal chromophores) directly within the retina. Consistent with pr...