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Concurrent management of multiple sclerosis and natalizumab-induced hepatitis with ofatumumab: a case report
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Pathology of Hepatocellular Carcinoma
Hepatocellular carcinoma is the most frequent primary malignant tumor of the liver. Its heterogeneity and biologic complexity determine numerous gross and microscopic patterns which we will examine together wi...
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Article
Open AccessMolecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver
Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify hepatic LAL protein content and activity in in vitro...
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Article
Open AccessHyperspectral evaluation of hepatic oxygenation in a model of total vs. arterial liver ischaemia
Liver ischaemia reperfusion injury (IRI) is a dreaded pathophysiological complication which may lead to an impaired liver function. The level of oxygen hypoperfusion affects the level of cellular damage during...
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Open AccessPublisher Correction: Liver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessLiver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C
The sinusoidal endothelial cells present in the liver (LSECs) are tipically characterized by the presence of pores (fenestrae). During some pathological conditions LSECs undergo “capillarization”, a process ch...
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Open AccessAlpha, Beta, gamma human PapillomaViruses (HPV) detection with a different sets of primers in oropharyngeal swabs, anal and cervical samples
Recent studies have shown a 13-fold increase of oropharyngeal cancer in the presence of HPV, while α-HPV detection seems to be rare in oral cavity in comparison to anal or cervical district, many novel β and γ...
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Open AccessNon-alcoholic fatty liver disease severity is modulated by transglutaminase type 2
Non-alcoholic fatty liver disease (NAFLD) is one of the most important liver diseases worldwide. Currently, no effective treatment is available, and NAFLD pathogenesis is incompletely understood. Transglutamin...
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Open AccessOral human Papillomavirus DNA detection in HIV-positive men: prevalence, predictors, and co-occurrence at anal site
HIV-positive patients carry an increased risk of HPV infection and associated cancers. Therefore, prevalence and patterns of HPV infection at different anatomical sites, as well as theoretical protection of no...
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Case report: human papilloma virus type 120-related papillomatosis mimicking laryngeal carcinoma
The relationship between human papilloma virus (HPV) and upper respiratory tract pathology was better understood in recent years and represents now an issue of particular interest in carcinogenesis and in immu...
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Open AccessBrain localization of Kaposi’s sarcoma in a patient treated by combination antiretroviral therapy
Central nervous system is a very rare site of Kaposi’s sarcoma in acquired immunodeficiency syndrome. Kaposi’s sarcoma, a neoplasm of endothelial origin, occurs mainly in the skin, but can involve many tissues...
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Open AccessAcute hepatocellular and cholestatic injury during therapy with hydrochlorothiazide - clinicohistopathologic findings: a case report
Hydrochlorothiazide and thiazide-like diuretics are considered first-line drugs for initial therapy in uncomplicated arterial hypertension. Acute cholecystitis is a well-known complication during treatment wit...
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Oral focal mucinosis of the Tongue
Oral focal mucinosis (OFM) is an uncommon clinicopathological entity which is considered to be the oral counterpart of cutaneous focal mucinosis and cutaneous myxoid cyst. It is comprised of a clinically eleva...
