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Article
Altered nuclear architecture in blood cells from Huntington’s disease patients
Cell nuclear architecture has been explored in cancer and laminopathies but not in neurodegenerative disorders. Huntington’s disease (HD) is a neurodegenerative disorder that leads to neuronal death. Chromosom...
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Article
Open AccessNAD+ improves neuromuscular development in a zebrafish model of FKRP-associated dystroglycanopathy
Secondary dystroglycanopathies are muscular dystrophies that result from mutations in genes that participate in Dystroglycan glycosylation. Glycosylation of Dystroglycan is essential for muscle fibers to adher...
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Chapter and Conference Paper
A Wavelet-Based Method for Multifractal Analysis of Medical Signals: Application to Dynamic Infrared Thermograms of Breast Cancer
We use the wavelet transform modulus maxima (WTMM) method to perform multifractal analysis of the temporal fluctuations of breast skin temperature recorded using infrared (IR) thermography. When investigating ...
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Article
Perinuclear distribution of heterochromatin in develo** C. elegans embryos
Specific nuclear domains are nonrandomly positioned within the nuclear space, and this preferential positioning has been shown to play an important role in genome activity and stability. Well-known examples in...
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Article
Automated Detection of Coronal Loops Using a Wavelet Transform Modulus Maxima Method
We propose and test a wavelet transform modulus maxima method for the automated detection and extraction of coronal loops in extreme ultraviolet images of the solar corona. This method decomposes an image into...
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Article
Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells
Radiation exposure is an occupational hazard for military personnel, some health care professionals, airport security screeners, and medical patients, with some individuals at risk for acute, high-dose exposur...
