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    Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production

    Phospholipids, the most abundant membrane lipid components, are crucial in maintaining membrane structures and homeostasis for biofunctions. As a structurally diverse and tightly regulated system involved in m...

    Yi Liu, Quanli Liu, Anastasia Krivoruchko, Sakda Khoomrung in Nature Chemical Biology (2020)

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    Expanding the product portfolio of fungal type I fatty acid synthases

    Integration of heterologous enzymes into the reaction chambers of fungal fatty acid synthases (FASs) demonstrates the capacity of these megaenzymes for engineered production of short- and medium-chain fatty ac...

    Zhiwei Zhu, Yong** J Zhou, Anastasia Krivoruchko in Nature Chemical Biology (2017)