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Open AccessSpatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum
Plasmodium falciparum has repeatedly evolved resistance to first-line anti-malarial drugs, thwarting efforts to control and eliminate the disease and in some period of time this contributed largely to an increase...
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Article
Open AccessThe distribution of haemoglobin C and its prevalence in newborns in Africa
Haemoglobin C (HbC) is one of the commonest structural haemoglobin variants in human populations. Although HbC causes mild clinical complications, its diagnosis and genetic counselling are important to prevent...
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Article
Open AccessA global map of dominant malaria vectors
Global maps, in particular those based on vector distributions, have long been used to help visualise the global extent of malaria. Few, however, have been created with the support of a comprehensive and exten...
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Open AccessA new world malaria map: Plasmodium falciparum endemicity in 2010
Transmission intensity affects almost all aspects of malaria epidemiology and the impact of malaria on human populations. Maps of transmission intensity are necessary to identify populations at different level...
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Open AccessErratum to: The dominant Anopheles vectors of human malaria in the Americas: occurrence data, distribution maps and bionomic précis
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Open AccessTravel risk, malaria importation and malaria transmission in Zanzibar
The prevalence of Plasmodium falciparum malaria in Zanzibar has reached historic lows. Improving control requires quantifying malaria importation rates, identifying high-risk travelers and assessing onwards trans...
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Open AccessModelling the global constraints of temperature on transmission of Plasmodium falciparum and P. vivax
Temperature is a key determinant of environmental suitability for transmission of human malaria, modulating endemicity in some regions and preventing transmission in others. The spatial modelling of malaria en...
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Open AccessThe dominant Anopheles vectors of human malaria in the Asia-Pacific region: occurrence data, distribution maps and bionomic précis
The final article in a series of three publications examining the global distribution of 41 dominant vector species (DVS) of malaria is presented here. The first publication examined the DVS from the Americas,...
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Open AccessThe global distribution of the Duffy blood group
Blood group variants are characteristic of population groups, and can show conspicuous geographic patterns. Interest in the global prevalence of the Duffy blood group variants is multidisciplinary, but of part...
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Open AccessThe dominant Anopheles vectors of human malaria in Africa, Europe and the Middle East: occurrence data, distribution maps and bionomic précis
This is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human malaria. The first paper addressed the DVS of the Americas and the third ...
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Open AccessGlobal distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis
It has been 100 years since the first report of sickle haemoglobin (HbS). More than 50 years ago, it was suggested that the gene responsible for this disorder could reach high frequencies because of resistance...
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Open AccessThe dominant Anopheles vectors of human malaria in the Americas: occurrence data, distribution maps and bionomic précis
An increasing knowledge of the global risk of malaria shows that the nations of the Americas have the lowest levels of Plasmodium falciparum and P. vivax endemicity worldwide, sustained, in part, by substantive i...
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Climate change and the global malaria recession
A comparison of a recently published evidence-based map of the distribution of the Plasmodium falciparum malaria parasite with data from 1900, before the introduction of major malaria control measures, suggests t...
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Open AccessThe risks of malaria infection in Kenya in 2009
To design an effective strategy for the control of malaria requires a map of infection and disease risks to select appropriate suites of interventions. Advances in model based geo-statistics and malaria parasi...
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Open AccessDefining the relationship between Plasmodium falciparum parasite rate and clinical disease: statistical models for disease burden estimation
Clinical malaria has proven an elusive burden to enumerate. Many cases go undetected by routine disease recording systems. Epidemiologists have, therefore, frequently defaulted to actively measuring malaria in...
