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    Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation

    Xenopus RINGO/Speedy (XRINGO) is a potent inducer of oocyte meiotic maturation that can directly activate Cdk1 and Cdk2. Here, we show that endogenous XRINGO protein accumulates transiently during meiosis I entry...

    Gustavo J. Gutierrez, Andrea Vögtlin, Ana Castro, Ingvar Ferby in Nature Cell Biology (2006)