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  1. Article

    Open Access

    Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells

    Defining the mechanisms safeguarding cell fate identity in differentiated cells is crucial to improve 1) - our understanding of how differentiation is maintained in healthy tissues or altered in a disease stat...

    Maria A. Missinato, Sean Murphy, Michaela Lynott, Michael S. Yu in Nature Communications (2023)

  2. Article

    Open Access

    PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

    Cardiomyocytes undergo significant structural and functional changes after birth, and these fundamental processes are essential for the heart to pump blood to the growing body. However, due to the challenges o...

    Sean A. Murphy, Matthew Miyamoto, Anaïs Kervadec, Suraj Kannan in Nature Communications (2021)