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Article
Erratum: T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α
Nature Immunology 7, 1166–1173 (2006); published online 8 October 2006; corrected after print 3 November 2006 In the version of this article initially published, the equal contribution of the third author was ...
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Article
T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α
T cell anergy has been correlated with defective signaling by the GTPase Ras, but causal and mechanistic data linking defective Ras activity with T cell anergy are lacking. Here we used adenoviral transduction...
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Article
Tumor progression despite massive influx of activated CD8+ T cells in a patient with malignant melanoma ascites
Although melanoma tumors usually express antigens that can be recognized by T cells, immune-mediated tumor rejection is rare. In many cases this is despite the presence of high frequencies of circulating tumor...
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Article
A randomized phase II trial of interleukin-2 in combination with four different doses of bryostatin-1 in patients with renal cell carcinoma
Purpose: Bryostatin-1 is a PKC modulator with direct anti-tumor activity and immunomodulatory properties. We combined different doses of Bryostatin-1 with IL-2 to determine effects on cli...
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Protocol
Amplification with Arbitrary Primers
Several methods have been published that rely on the use of short oligonucleotide primers with arbitrary sequences to amplify discrete DNA fragments by the polymerase chain reaction (PCR) (1,2). Typically, a sing...
