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Article

Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A

Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it mediates Na⁺-dependent uptake of ω−3 fatty acids in th...

Shana Bergman, Rosemary J. Cater, Ambrose Plante, Filippo Mancia… in Nature Communications (2023)