14 Result(s)

Article

A cross-sectional study of asymptomatic Plasmodium falciparum infection burden and risk factors in general population children in 12 villages in northern Uganda

Plasmodium falciparum malaria is an important cause of morbidity in northern Uganda. This study was undertaken to assess village-, household-, and individual-level risk factors of asymptomatic falciparum malaria ...

Marlena Maziarz, Hadijah Nabalende, Isaac Otim, Ismail D. Legason… in Malaria Journal (2018)

Article

“We were being treated like the Queen”: understanding trial factors influencing high paediatric malaria treatment adherence in western Kenya

Adherence to anti-malarial medication is highly variable but frequently suboptimal. Numerous interventions with a variety of methodological approaches have been implemented to address the problem. A recently c...

Caroline Jones, Ambrose O. Talisuna, Robert W. Snow, Dejan Zurovac in Malaria Journal (2018)

Article

Intravenous artesunate plus Artemisnin based Combination Therapy (ACT) or intravenous quinine plus ACT for treatment of severe malaria in Ugandan children: a randomized controlled clinical trial

Severe malaria is a medical emergency associated with high mortality. Adequate treatment requires initial parenteral therapy for fast parasite clearance followed by longer acting oral antimalarial drugs for cu...

Pauline Byakika-Kibwika, Jane Achan, Mohammed Lamorde… in BMC Infectious Diseases (2017)

Article

Age and geographic patterns of Plasmodium falciparum malaria infection in a representative sample of children living in Burkitt lymphoma-endemic areas of northern Uganda

Falciparum malaria is an important risk factor for African Burkitt lymphoma (BL), but few studies have evaluated malaria patterns in healthy BL-age children in populations where both diseases are endemic. To o...

Marlena Maziarz, Tobias Kinyera, Isaac Otim, Paul Kagwa… in Malaria Journal (2017)

Article

Efficacy of text-message reminders on paediatric malaria treatment adherence and their post-treatment return to health facilities in Kenya: a randomized controlled trial

Short Message Service (SMS) reminders have been suggested as a potential intervention for improving adherence to medications and health facility attendance.

Ambrose O. Talisuna, Amos Oburu, Sophie Githinji, Josephine Malinga… in Malaria Journal (2017)

Article

The past, present and future use of epidemiological intelligence to plan malaria vector control and parasite prevention in Uganda

An important prelude to develo** strategies to control infectious diseases is a detailed epidemiological evidence platform to target cost-effective interventions and define resource needs.

Ambrose O Talisuna, Abdisalan M Noor, Albert P Okui, Robert W Snow in Malaria Journal (2015)

Article

The affordable medicines facility-malaria—A success in peril

The Affordable Medicines Facility-malaria (AMFm) has put into place a bold financing plan for artemisinin-combination therapy in a pilot phase in seven countries covering half the population at risk of malaria...

Ambrose O Talisuna, Seraphine Adibaku, Chioma N Amojah, George K Amofah… in Malaria Journal (2012)

Article

Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study

Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in the private sector, the first port of call for most mala...

Ambrose O Talisuna, Penny Grewal Daumerie, Andrew Balyeku, Timothy Egan… in Malaria Journal (2012)

Article

Overcoming the affordability barrier for effective and high quality life saving malaria medicines in the private sector in rural Uganda: the Consortium for ACT Private Sector Subsidy (CAPSS) pilot study

Ambrose O Talisuna, Penny Grevval, Andrew Balyeku, Timothy Egan… in Malaria Journal (2012)

Article

Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria

Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex do...

Jane Achan, Ambrose O Talisuna, Annette Erhart, Adoke Yeka… in Malaria Journal (2011)

Article

Monitoring antimalarial safety and tolerability in clinical trials: A case study from Uganda

New antimalarial regimens, including artemisinin-based combination therapies (ACTs), have been adopted widely as first-line treatment for uncomplicated malaria. Although these drugs appear to be safe and well-...

Sarah G Staedke, Prasanna Jagannathan, Adoke Yeka, Hasifa Bukirwa… in Malaria Journal (2008)

Article

Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children

Combination antimalarial therapy is recommended for the treatment of uncomplicated falciparum malaria in Africa; however, some concerns about the safety and tolerability of new regimens remain. This study compare...

Catherine Maiteki-Sebuguzi, Prasanna Jagannathan, Vincent M Yau… in Malaria Journal (2008)

Article

Caregivers' perceived treatment failure in home-based management of fever among Ugandan children aged less than five years

Home-based management of fever (HBMF) could improve prompt access to antimalarial medicines for African children. However, the perception of treatment failure by caregivers has not been assessed.

Mugagga Malimbo, Erieza Mugisha, Fred Kato, Charles Karamagi… in Malaria Journal (2006)

Article

Pharmacovigilance of antimalarial treatment in Africa: is it possible?

Pharmacovigilance, defined as "the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other possible drug related problem", is increasingly bei...

Ambrose O Talisuna, Sarah G Staedke, Umberto D'Alessandro in Malaria Journal (2006)