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Article
Open AccessTwo Metallic Nanoparticles Formulas of Phyllostachys heterocycla Extract Exhibited Potent Cytotoxicity against Ovarian Cancer Cells through Apoptosis Induction
Phyllostachys heterocycla is well-known for its high diversity of bioactive metabolites, which are the reason for its various potential medical uses for which anticancer activity has been proven. Herein, Phyllost...
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Article
Open AccessFast Sensitive and Accurate Analysis of the Most Common Synthetic Food Colorants in 65 Egyptian Commercial Products Using New HPLC–DAD and UPLC-ESI–MS/MS Methods
Overexposure to food colorants above the allowed daily intake (ADI) level can provoke hyperactivity and other disturbed behaviors especially in children. Two new methods were developed to separate five synthet...
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Article
Seasonal Variations in Antioxidant Components of Olea europaea in Leaves of Different Cultivars, Seasons, and Oil Products in Sinai
A mixture experimental design resulted in water-ethanol mixture to replace toxic extractants used to date and enhance greenness of extraction procedure. Oleuropein (OLP) and tyrosol (TYR) contents, in leaves f...
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Article
Anxiolytic and anticonvulsant activity followed by molecular docking study of ceramides from the Red Sea sponge Negombata sp
The chemical investigation of the Red Sea sponge Negombata sp. led to isolation and structure elucidation of five new ceramides N ((2S,3R,4E,8E)-1,3-dihydroxyhexacosa-4,8-dien-2-yl)pentadecanamide (1), N-((2S,3R,
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Article
A Developed High-Performance Thin-Layer Chromatographic Method for the Determination of Orlistat in Pharmaceutical Preparations
A sensitive and simple high-performance thin-layer chromatographic method is developed and validated according to the International Conference on Harmonisation (ICH) guidelines. The procedure was applied for t...
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Article
Correction to: Cytotoxic and anti-inflammatory compounds from Red Sea grass Thalassodendron ciliatum
The original version of this article unfortunately contained a mistake in the Electronic Supplementary Material.
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Article
Cytotoxic and anti-inflammatory compounds from Red Sea grass Thalassodendron ciliatum
Chemical investigation of the less polar fraction methylene dichloride–methanol extract of the Red Sea grass Thalassodendron ciliatum led to the isolation of a new phytoceramide molecular species TCC-1, along wit...
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Article
Cytotoxic activity evaluation and molecular docking study of phenolic derivatives from Achillea fragrantissima (Forssk.) growing in Egypt
Achillea fragrantissima (Forssk) Sch. Bip. (Asteraceae) is one of the most important medicinal plant species in Egypt. Phytochemical investigation of the methanolic extract of A. fragrant...
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Article
Cytotoxic ceramides from the Red Sea sponge Spheciospongia vagabunda
Extracts of Egyptian marine organisms from the Red Sea were screened for their anticancer activity using sulforhodamine B assay. The extract of the Red Sea sponge Spheciospongia vagabunda possessed promising ant...
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Article
Improved silymarin content in elicited multiple shoot cultures of Silybum marianum L.
Silybum marianum L. extracts are being used as antihepatotoxic therapy for liver diseases. Silymarin is a polyphenolic flavonoid mixture isolated from milk thistle which is believed to be respons...