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Article
Results of the First Double Blind Placebo (Pl) Controlled Study of Caffeine Citrate (Cc) for the Treatment of Apnea of Prematurity (Aop) † 1001
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Article
Caffeine Pharmacokinetics (PK) In Premature Infants With Apnea of Prematurity(AOP) 340
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Article
447 THE EFFECT OF POST-NATAL AGE ON THE RESPONSE OF THE PITUTITARY-THYROID AXIS TO THYROTROPIN RELEASING HORMONE
Transient hypothyroxinemia is a common problem in the preterm infant. The response of the pituitary-thyroid (P-T) axis to exogenous thyrotropin releasing hormone (TRH) infusion has been used to confirm the eut...
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Article
Pulmonary Superoxide Dismutase Activity in the Euthyroid and Hypothyroid Ovine Fetus
Summary: Pulmonary superoxide dismutase (SOD) activity was measured in 11 euthyroid and 15 hypothyroid ovine fetuses at 130 days gestation. In the euthyroid fetus, the mean pulmonary SOD activity was similar i...
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Article
240 THYROTROPIN RELEASING HORMONE (TRH) AND OVINE FETAL LUNG (L) MATURATION
The role of TRH on ovine fetal L maturation was studied in 12 euthyroid fetuses (F). Beginning at 127 days, 6 F received 3 daily bolus IV injections (I) of 50 ug TRH and 6 control F received saline (S). All we...
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Article
1244 EFFECTS OF A DOUBLE-WALLED INCUBATOR ON THE PARTITION OF BODY HEAT LOSS OF PREMATURE INFANTS
We measured metabolic heat production (M) and body heat loss (HL) of 8 AGA premature infants by indirect calorimetry in a double-walled incubator (Air-Shields) with (DW) and without (SW) the inner wall. The in...
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Article
1650 THE EFFECT OF BETAMETHASONE (B) AND THYROTROPIN RE- LEASING HORMONE (T) ON LUNG (L) ANTI-OXIDANT ENZYME LEVElS IN THE FETAL (F) RABBIT
In the adult, administration of exogenous thyroxine or corticosteriods is associated with enhanced development of L oxygen toxicity. To determine if pharmacologic acceleration of F L maturation influences the ...
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Article
639 THE EFFECTS OF FORMULA (F) COMPOSITION AND VOLUME ON GASTRIC EMPTYING PATTERNS (GEP) IN THE PRETERM INFANT (PI)
GEP may be influenced by the test meal volume (V) and its composition. To determine the effects of F composition and V on GEP, 4 PI, 1.3-1.7 kg, were fed consecutive alternate feedings of Similac 24 (S) or LBW...
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Article
The Effect of Fetal Thyroidectomy on Ovine Fetal Lung Maturation
Summary: Studies were conducted to assess the effect of fetal thyroidectomy early in the third trimester on lung growth and surfactant maturation in the sheep. At 95–99 days of gestation, a fetal thyroidectomy...
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Article
182 PLACENTAL IMPERMEABILITY TO PARATHORMONE (PTH) 1–125 IN THE EWE
Studies altering plasma calcium levels have demonstrated that the maternal (M) and fetal (F) parathyroid glands appear to function automonously and suggest a lack of placental permeability to PTH. To determine...
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Article
295 SERUM THYROID STIMULATING HORMONE (TSH), THYROXINE (T4) AND TRIIODOTHYRONINE (T3) LEVELS IN THE PRE-TERM INFANT
To determine if inclusion of the healthy pre-term infant in mass neonatal screening programs would increase the number of false-positive results, the changes in serum TSH, T4 and T3 levels were studied in healthy...
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Article
181 THE EFFECT OF HALOTHANE (H) ON THYROID AND HEPATIC FUNCTION IN THE PREGNANT EWE
To evaluate the effect of H and surgery on thyroid and hepatic function in the pregnant sheep, 14 date bred ewes from 104 to 134 days gestation were anesthetized with 0.5 to 1.5% H in nitrous oxide and oxygen....
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Article
1178 PULMONARY SUPEROXIDE DISMUTASE (PSOD) ACTIVITY IN THE EUTHYROID (E) AND ATHYROTIC (Tx) OVINE FETUS
Animal studies have shown that the development of pulmonary oxygen toxicity is enhanced in the hyperthyroid and delayed in the hypothyroid state. PSOD activity was studied in 5 E at 130 and 5 E at 140 days (d)...
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Article
THE EFFECT OF FETAL THYROIDECTOMY ON OVINE FETAL LUNG MATURATION
Previous studies have shown that thyroxine is one of the factors which influences fetal lung maturation. To further delineate the role of the thyroid hormones, ovine fetuses were surgically thyroidectomized at...
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Article
THE EFFECT OF PERINATAL FACTORS ON CORD THYROXINE (T4) CONCENTRATION
To evaluate the effect of various perinatal factors, 4,068 cord samples were assayed for T4 concentration, and each chart reviewed for the following factors: Cesarean section (CS), prolonged rupture of membran...
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Article
VASOPRESSIN RELEASE IN THE LAMB FETUS
Arginine vasopressin (AVP) release was studied in 16 chronic fetal preparations between 101 and 141 days gestation following the infusion of 5% NaCl. The mean baseline plasma AVP in fetuses from 101-120 (N=20)...
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Article
Insulin-Glucagon Substrate Interrelations in the Fetal Sheep
Extract: Twenty-four studies were conducted in 14 sheep fetuses to investigate the pancreatic islet α and β cell responses to substrate infusions. The studies were conducted between 100 days gestation and near...