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Open AccessPerspectives and Behaviors of People with Diabetes toward Time in Range and Glucose Control in Diabetes Management: An Online Survey
This study assessed experiences, attitudes, and behaviors of people with diabetes (PwD) regarding diabetes self-management and glucose control, and their level of awareness, knowledge, and attitudes toward tim...
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Open AccessEmotional, Psychological, and Social Well-being Experience of Long-Term Living with Type 1 Diabetes Mellitus: A Patient–Psychiatrist–Endocrinologist Perspective
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease that impacts blood glucose levels and can also lead to an increased prevalence of psychiatric conditions. Living with T1DM has been associated wi...
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Open AccessImpact of Living with Stigma in Persons with Type 1 Diabetes: A Patient–Physician Perspective
Type 1 diabetes mellitus (T1D) is an autoimmune disorder characterized by a complete deficiency in insulin due to the destruction of pancreatic beta cells. Globally, T1D accounts for nearly 5–10% of the total ...
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Therapeutic inertia in type 2 diabetes mellitus: a fine line between advancing and de-intensifying
Type 2 diabetes mellitus is a progressive disease requiring regular monitoring and therapeutic changes. It is important that healthcare professionals embrace both ends of the spectrum of therapeutic inertia, i...
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Open AccessHealthcare Professionals’ Knowledge of and Attitudes Towards the Use of Time in Range in Diabetes Management: Online Survey Across Seven Countries
Time in range (TIR) is a metric of glycaemic target management derived from continuous glucose monitoring (CGM) data. This study aimed to understand knowledge of and attitudes towards use of TIR among healthca...
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Applying the WHO global targets for diabetes mellitus
In 2022, the WHO created the first global targets for diabetes mellitus. The targets are that by 2030, 80% of people living with diabetes mellitus are diagnosed, and that 80% of those living with diabetes mell...
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Insulin: evolution of insulin formulations and their application in clinical practice over 100 years
The first preparation of insulin extracted from a pancreas and made suitable for use in humans after purification was achieved 100 years ago in Toronto, an epoch-making achievement, which has ultimately provid...
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Open AccessThe Safety and Efficacy of Second-Generation Basal Insulin Analogues in Adults with Type 2 Diabetes at Risk of Hypoglycemia and Use in Other Special Populations: A Narrative Review
Hypoglycemia is a major barrier impeding glycemic control in persons with type 2 diabetes mellitus and creates a substantial burden on the healthcare system. Certain populations that require special attention,...
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Open AccessDifferentiating Basal Insulin Preparations: Understanding How They Work Explains Why They Are Different
Since the introduction of insulin as a life-saving agent for patients with type 1 diabetes, insulin preparations have evolved to approximate physiologic insulin delivery profiles to meet prandial and basal in...
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Diabetes and cardiovascular disease: The role of glycemic control
Over the past decade, clinical practice guidelines have lowered their glycemic targets for people with type 2 diabetes. However, recent randomized controlled trials (ACCORD, ADVANCE, and VADT) demonstrate that...
