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  1. Article

    Open Access

    The reticular lamina and basilar membrane vibrations in the transverse direction in the basal turn of the living gerbil cochlea

    The prevailing theory of cochlear function states that outer hair cells amplify sound-induced vibration to improve hearing sensitivity and frequency specificity. Recent micromechanical measurements in the basa...

    Wenxuan He, George Burwood, Edward V. Porsov, Anders Fridberger in Scientific Reports (2022)

  2. Article

    Open Access

    The mechanoelectrical transducer channel is not required for regulation of cochlear blood flow during loud sound exposure in mice

    The mammalian cochlea possesses unique acoustic sensitivity due to a mechanoelectrical ‘amplifier’, which requires the metabolic support of the cochlear lateral wall. Loud sound exposure sufficient to induce p...

    George W. S. Burwood, Suzan Dziennis, Teresa Wilson, Sarah Foster in Scientific Reports (2020)

  3. Article

    Open Access

    A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

    To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but ...

    Alfred L. Nuttall, Anthony J. Ricci, George Burwood in Nature Communications (2018)

  4. Article

    Open Access

    Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function

    The phospholipid- and Ca2+-binding protein annexin A5 (ANXA5) is the most abundant membrane-associated protein of ~P23 mouse vestibular hair bundles, the inner ear’s sensory organelle. Using quantitative mass spe...

    Jocelyn F. Krey, Meghan Drummond, Sarah Foster, Edward Porsov in Scientific Reports (2016)