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Article
Open AccessOxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients
Oxytocin (OXT) is a neuropeptide and hormone involved in emotional functioning and also seems to play a role in moderating the stress response. Both preclinical and clinical studies point to an increased methy...
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Article
Open AccessThe benefit of an ambulant psychiatric rehabilitation program in Vienna, Austria: an uncontrolled repeated measures study
We investigated the benefit of a 6-week ambulant psychiatric rehabilitation program in an ambulant psychiatric rehabilitation clinic in Vienna, Austria, from January 2014 to December 2016 by an uncontrolled re...
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Article
Open AccessEvaluation eines naturalistischen verhaltenstherapeutischen Rehabilitations-Settings
Zahlreiche Studien belegen, dass Psychotherapie wirkt. Sie findet in unterschiedlichsten Settings statt, die Datenlage dazu ist derzeit in Österreich noch ausbaufähig. Verhaltenstherapie stellt im 6‑wöchigen K...
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Article
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and serious illness1, affecting 0.9–4% of women and 0.3% of men2–4, with twin-based heritability estimates of 50–60%5. Mortality rat...
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Article
Open AccessThe Impact of COMT and Childhood Maltreatment on Suicidal Behaviour in Affective Disorders
The inconsistent findings on the association between COMT (catecholamine-O-methyl-transferase) and suicidal behaviour gave reason to choose a clear phenotype description of suicidal behaviour and take childhoo...
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Article
Einstellung zu antidepressiver Therapie: Akzeptanz vs. Stigmatisierung
Die aktuelle Studie untersucht die Einstel-lung zu antidepressiver Therapie der Allgemeinbevöl-kerung.
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Article
The “DGPPN-Cohort”: a national collaboration initiative by the German Association for Psychiatry and Psychotherapy (DGPPN) for establishing a large-scale cohort of psychiatric patients
The German Association for Psychiatry and Psychotherapy (DGPPN) has committed itself to establish a prospective national cohort of patients with major psychiatric disorders, the so-called DGPPN-Cohort. This pr...
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Article
The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk—a European multicentre study on treatment-resistant major depressive disorder
Recently published data have reported associations between cytochrome P450 metabolizer status and suicidality. The aim of our study was to investigate the role of genetic polymorphisms of the cytochrome P450 g...
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Article
Open AccessUtility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays
We report an attempt to extend the previously successful approach of combining SNP (single nucleotide polymorphism) microarrays and DNA pooling (SNP-MaP) employing high-density microarrays. Whereas earlier stu...
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Article
In search of susceptibility genes for schizophrenia
After the recent discovery and replication of several schizophrenia candidate regions on multiple chromosomes, susceptibility genes for schizophrenia could be identified for the first time. Each of these disco...
