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Article
Open AccessA deep learning algorithm to predict risk of pancreatic cancer from disease trajectories
Pancreatic cancer is an aggressive disease that typically presents late with poor outcomes, indicating a pronounced need for early detection. In this study, we applied artificial intelligence methods to clinic...
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Article
Open AccessMolecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics
Poly (ADP)-ribose polymerase (PARP) inhibitors have entered routine clinical practice for the treatment of high-grade serous ovarian cancer (HGSOC), yet the molecular mechanisms underlying treatment response t...
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Article
Open AccessTowards general network architecture design criteria for negative gas adsorption transitions in ultraporous frameworks
Switchable metal-organic frameworks (MOFs) have been proposed for various energy-related storage and separation applications, but the mechanistic understanding of adsorption-induced switching transitions is st...
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Article
From talc to enstatite: archaeometric investigations on an ancient Egyptian whitish bead
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Article
Open AccessThermodynamic potential and phase diagram for multiferroic bismuth ferrite (BiFeO 3 )
We construct a Landau–Ginzburg thermodynamic potential, and the corresponding phase diagram for pristine and slightly doped bismuth ferrite, a ferroelectric antiferromagnet at room temperature. The potential i...
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Article
Open AccessThe intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
Human endogenous retroviruses (HERVs) constitute 8% of the human genome and contribute substantially to the transcriptome. HERVs have been shown to generate RNAs that modulate host gene expression. However, ex...
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Article
Fractal Dimension and Maximum Roughness Applied as Sculpture Descriptor for Tektites
X-ray computed tomography (three-dimensional μ-CT) as a non-destructive method is applied to a geological investigation. This technique is applied to the analysis of twelve tektites which provides detailed ima...
