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Chapter and Conference Paper
Contact Conditions and Temperature Distribution During Cryogenic Deep Drawing with Macro-structured Tools
In this paper, the process model for cryogenic forming with macro-structured tools is analyzed regarding the continuously changing thermal conditions during the deep drawing process. For this purpose, the tran...
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Article
Open AccessMulticenter comparison of transcatheter aortic valve implantation with the self-expanding ACURATE neo2 versus Evolut PRO transcatheter heart valves
New-generation self-expanding transcatheter aortic heart valves (THV) were designed to overcome technical constraints of their preceding generations. We sought to compare the efficacy and safety of the self-ex...
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Article
Open AccessMethods for integrating postural control into biomechanical human simulations: a systematic review
Understanding of the human body’s internal processes to maintain balance is fundamental to simulate postural control behaviour. The body uses multiple sensory systems’ information to obtain a reliable estimate...
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Article
Open AccessSubject-specific tribo-contact conditions in total knee replacements: a simulation framework across scales
Fundamental knowledge about in vivo kinematics and contact conditions at the articulating interfaces of total knee replacements are essential for predicting and optimizing their behavior and durability. Howeve...
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Article
Linear scalability of dense-pattern Herriott-type multipass cell design
Multipass cells (MPC) have been widely used for high-sensitivity spectroscopic measurements. We report the linear scalability in the configuration design of an MPC, which is derived from ray transfer equations in...
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Chapter and Conference Paper
Additive Manufacturing of a Laser Heat Sink: Multiphysical Simulation for Thermal Material Requirement Derivation
Heat dissipation inside diode-pumped Nd:YVO4 laser crystals requires an efficient cooling concept to reduce heat-induced stress and thus to avoid the mechanical destruction of the laser medium. Due to a high degr...
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Chapter
Proactive Integration of User Data into Engineering Processes—A Generic Approach and Specific Examples
User-centered design ( ) describes an approach, which aims to increase customer satisfaction, , usability, user experience, and perceived by enhancing the fit between products and their users in the respe...
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Article
Cholesterinsenkende Therapie bei älteren Patienten
LDL(low density lipoprotein)-Cholesterin-senkende Therapien stellen einen etablierten Therapiebaustein in der kardiovaskulären Prävention dar. Für jüngere Patienten existiert eine breite Evidenz, die belegt, d...
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Article
Open AccessSymptom burden correlates to impairment of diffusion capacity and exercise intolerance in long COVID patients
After acute infection with the SARS-CoV-2 virus, a considerable number of patients remains symptomatic with pathological changes in various organ systems. This study aimed to relate the physical and mental bur...
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Article
Open AccessThe impact of the COVID-19 pandemic on non-COVID induced sepsis survival
The COVID-19 pandemic has taken a toll on health care systems worldwide, which has led to increased mortality of different diseases like myocardial infarction. This is most likely due to three factors. First, ...
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Chapter and Conference Paper
Simplifying Ergonomic Assessment for Designers: A User-Product Interaction-Modelling Framework in CAD
Digital human models have not yet reached their full potential for proactive virtual assessment of ergonomics in engineering and industrial design. Especially the modelling of interaction between user and prod...
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Article
Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have shown high efficacy, but immunocompromised participants were excluded from controlled clinical trials. In this study, we compa...
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Article
Open AccessDoes a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone: a systematic review and meta-analysis
In anesthesia, additive drug interactions are used for reducing dose and dose-dependent side-effects. The combination of propofol with volatile anesthetics is rather unusual but might have advantages compared ...
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Chapter and Conference Paper
A New Non-destructive Testing Method Applied to Clinching
To pursue better quality, there is a strong need for efficient and robust non-destructive testing methods for joining processes. A new approach has been proposed to detect loose bolted joints using acoustic wa...
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Chapter and Conference Paper
Segmentation of Musculotendinous Structures of the Hip from 3D Imaging for Patient-Specific Individualization of Biomechanical Simulations
Due to a steady increase of total hip arthroplasty, biomechanical multibody simulations are moving more and more into focus. These simulations allow to calculate forces, moments and muscle activities in the hu...
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Chapter and Conference Paper
Materialcharakterisierung transparenter Kunststoffe für die Additive Fertigung
Additive Fertigungsverfahren ermöglichen eine kosteneffiziente Herstellung von hochintegrierten Komponenten in kleiner Stückzahl. Im Rahmen dieser Untersuchung sollen die Potenziale der Additiven Fertigung am ...
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Article
A non-destructive testing method for joints by the measurement of the energy dissipation
The multi-material mix used nowadays requires several joints to establish a durable connection. It is necessary to test the joints without harming the parts to ensure the safety of the whole structure. Therefo...
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Chapter and Conference Paper
Biomechanical Digital Human Models: Chances and Challenges to Expand Ergonomic Evaluation
Nowadays, ergonomic evaluation of work can be done using Digital Human Models (DHM). One advantage is to reduce the need for corrective measures by supporting a more prospective ergonomic work design. Althoug...
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Article
Open AccessPhylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution
Translation of specific mRNAs can be highly regulated in different cells, tissues or under pathological conditions. Ribosome heterogeneity can originate from variable expression or post-translational modificat...
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Chapter
Correction to: Plant-Derived Drugs Affecting GPRCs
Chapter 7 in: A. Böttger et al., Lessons on Caffeine, Cannabis & Co, Learning Materials in Biosciences, https://doi.org/10.1007/978-3-319-99546-5_7