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  1. No Access

    Chapter and Conference Paper

    Contact Conditions and Temperature Distribution During Cryogenic Deep Drawing with Macro-structured Tools

    In this paper, the process model for cryogenic forming with macro-structured tools is analyzed regarding the continuously changing thermal conditions during the deep drawing process. For this purpose, the tran...

    Marc Tulke, Rémi Lafarge, Alexander Wolf in Proceedings of the 14th International Conf… (2024)

  2. Article

    Open Access

    Multicenter comparison of transcatheter aortic valve implantation with the self-expanding ACURATE neo2 versus Evolut PRO transcatheter heart valves

    New-generation self-expanding transcatheter aortic heart valves (THV) were designed to overcome technical constraints of their preceding generations. We sought to compare the efficacy and safety of the self-ex...

    Tobias Rheude, Costanza Pellegrini, Martin Landt in Clinical Research in Cardiology (2024)

  3. Article

    Open Access

    Methods for integrating postural control into biomechanical human simulations: a systematic review

    Understanding of the human body’s internal processes to maintain balance is fundamental to simulate postural control behaviour. The body uses multiple sensory systems’ information to obtain a reliable estimate...

    Julian Shanbhag, Alexander Wolf in Journal of NeuroEngineering and Rehabilita… (2023)

  4. Article

    Open Access

    Subject-specific tribo-contact conditions in total knee replacements: a simulation framework across scales

    Fundamental knowledge about in vivo kinematics and contact conditions at the articulating interfaces of total knee replacements are essential for predicting and optimizing their behavior and durability. Howeve...

    Benedict Rothammer, Alexander Wolf in Biomechanics and Modeling in Mechanobiology (2023)

  5. No Access

    Article

    Linear scalability of dense-pattern Herriott-type multipass cell design

    Multipass cells (MPC) have been widely used for high-sensitivity spectroscopic measurements. We report the linear scalability in the configuration design of an MPC, which is derived from ray transfer equations in...

    Junjun Wu, Tobias Grabe, Jan-Luca Götz, Joshua Trapp in Applied Physics B (2023)

  6. No Access

    Chapter and Conference Paper

    Additive Manufacturing of a Laser Heat Sink: Multiphysical Simulation for Thermal Material Requirement Derivation

    Heat dissipation inside diode-pumped Nd:YVO4 laser crystals requires an efficient cooling concept to reduce heat-induced stress and thus to avoid the mechanical destruction of the laser medium. Due to a high degr...

    Julian Röttger, Tobias Grabe in Innovative Product Development by Additive… (2023)

  7. No Access

    Chapter

    Proactive Integration of User Data into Engineering Processes—A Generic Approach and Specific Examples

    User-centered design ( ) describes an approach, which aims to increase customer satisfaction, , usability, user experience, and perceived by enhancing the fit between products and their users in the respe...

    Alexander Wolf, Tina Buker, Carla Molz, David Scherb in Human-Automation Interaction (2023)

  8. No Access

    Article

    Cholesterinsenkende Therapie bei älteren Patienten

    LDL(low density lipoprotein)-Cholesterin-senkende Therapien stellen einen etablierten Therapiebaustein in der kardiovaskulären Prävention dar. Für jüngere Patienten existiert eine breite Evidenz, die belegt, d...

    Prof. Dr. Harald Rittger, David M. Leistner, Roland Hardt, Markus Dörr in Die Kardiologie (2022)

  9. Article

    Open Access

    Symptom burden correlates to impairment of diffusion capacity and exercise intolerance in long COVID patients

    After acute infection with the SARS-CoV-2 virus, a considerable number of patients remains symptomatic with pathological changes in various organ systems. This study aimed to relate the physical and mental bur...

    Johannes Kersten, Alexander Wolf, Luis Hoyo, Elina Hüll in Scientific Reports (2022)

  10. Article

    Open Access

    The impact of the COVID-19 pandemic on non-COVID induced sepsis survival

    The COVID-19 pandemic has taken a toll on health care systems worldwide, which has led to increased mortality of different diseases like myocardial infarction. This is most likely due to three factors. First, ...

    Matthias Unterberg, Tim Rahmel, Katharina Rump, Alexander Wolf in BMC Anesthesiology (2022)

  11. No Access

    Chapter and Conference Paper

    Simplifying Ergonomic Assessment for Designers: A User-Product Interaction-Modelling Framework in CAD

    Digital human models have not yet reached their full potential for proactive virtual assessment of ergonomics in engineering and industrial design. Especially the modelling of interaction between user and prod...

    Alexander Wolf, Yvonne Wagner, Marius Oßwald in Proceedings of the 21st Congress of the In… (2022)

  12. Article

    Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors

    Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have shown high efficacy, but immunocompromised participants were excluded from controlled clinical trials. In this study, we compa...

    Rachna T. Shroff, Pavani Chalasani, Ran Wei, Daniel Pennington in Nature Medicine (2021)

  13. Article

    Open Access

    Does a combined intravenous-volatile anesthesia offer advantages compared to an intravenous or volatile anesthesia alone: a systematic review and meta-analysis

    In anesthesia, additive drug interactions are used for reducing dose and dose-dependent side-effects. The combination of propofol with volatile anesthetics is rather unusual but might have advantages compared ...

    Alexander Wolf, Helene Selpien, Helge Haberl, Matthias Unterberg in BMC Anesthesiology (2021)

  14. No Access

    Chapter and Conference Paper

    A New Non-destructive Testing Method Applied to Clinching

    To pursue better quality, there is a strong need for efficient and robust non-destructive testing methods for joining processes. A new approach has been proposed to detect loose bolted joints using acoustic wa...

    Rémi Lafarge, Alexander Wolf, Christina Guilleaume, Alexander Brosius in Forming the Future (2021)

  15. No Access

    Chapter and Conference Paper

    Segmentation of Musculotendinous Structures of the Hip from 3D Imaging for Patient-Specific Individualization of Biomechanical Simulations

    Due to a steady increase of total hip arthroplasty, biomechanical multibody simulations are moving more and more into focus. These simulations allow to calculate forces, moments and muscle activities in the hu...

    Christopher Fleischmann, David Scherb in Human Interaction, Emerging Technologies a… (2021)

  16. No Access

    Chapter and Conference Paper

    Materialcharakterisierung transparenter Kunststoffe für die Additive Fertigung

    Additive Fertigungsverfahren ermöglichen eine kosteneffiziente Herstellung von hochintegrierten Komponenten in kleiner Stückzahl. Im Rahmen dieser Untersuchung sollen die Potenziale der Additiven Fertigung am ...

    Katharina Rettschlag, Alexander Wolf in Konstruktion für die Additive Fertigung 20… (2020)

  17. No Access

    Article

    A non-destructive testing method for joints by the measurement of the energy dissipation

    The multi-material mix used nowadays requires several joints to establish a durable connection. It is necessary to test the joints without harming the parts to ensure the safety of the whole structure. Therefo...

    Alexander Wolf, Remi Lafarge, Alexander Brosius in Production Engineering (2019)

  18. No Access

    Chapter and Conference Paper

    Biomechanical Digital Human Models: Chances and Challenges to Expand Ergonomic Evaluation

    Nowadays, ergonomic evaluation of work can be done using Digital Human Models (DHM). One advantage is to reduce the need for corrective measures by supporting a more prospective ergonomic work design. Althoug...

    Markus Peters, Eric Quadrat, Alexander Nolte in Human Systems Engineering and Design (2019)

  19. Article

    Open Access

    Phylogenetic and genomic analyses of the ribosomal oxygenases Riox1 (No66) and Riox2 (Mina53) provide new insights into their evolution

    Translation of specific mRNAs can be highly regulated in different cells, tissues or under pathological conditions. Ribosome heterogeneity can originate from variable expression or post-translational modificat...

    Katharina E. Bräuer, Kevin Brockers, Jasmin Moneer in BMC Evolutionary Biology (2018)

  20. Chapter

    Correction to: Plant-Derived Drugs Affecting GPRCs

    Chapter 7 in: A. Böttger et al., Lessons on Caffeine, Cannabis & Co, Learning Materials in Biosciences, https://doi.org/10.1007/978-3-319-99546-5_7

    Angelika Böttger, Ute Vothknecht, Cordelia Bolle in Lessons on Caffeine, Cannabis & Co (2018)

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