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Article
Open AccessPoint of care parenchymal volume analyses to estimate split renal function and predict functional outcomes after radical nephrectomy
Accurate prediction of new baseline GFR (NBGFR) after radical nephrectomy (RN) can inform clinical management and patient counseling whenever RN is a strong consideration. Preoperative global GFR, split renal ...
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Article
Partial or radical nephrectomy for complex renal mass: a comparative analysis of oncological outcomes and complications from the ROSULA (Robotic Surgery for Large Renal Mass) Collaborative Group
To compare outcomes of robotic-assisted partial nephrectomy (RAPN) and minimally invasive radical nephrectomy (MIS-RN) for complex renal masses (CRM).
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Article
Review of Robotic-Assisted Radical Nephrectomy with Inferior Vena Cava Thrombectomy in Renal Cell Carcinoma
Recent advances in minimally invasive technology have compelled surgeons to perform nephrectomy with inferior vena cava thrombectomy using robotic assistance. Here, we aim to review the data comparing open ver...
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Chapter
Kidney Cancer and Its Treatment
Renal cell carcinoma (RCC) is the most common type of primary kidney neoplasm. Though most masses are found incidentally and are asymptomatic, patients can still present with the classic triad of RCC – flank p...
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Article
Extraluminal Duodenal Gangliocytic Paraganglioma Presenting with Intractable Back Pain in a Patient with End-Stage Renal Disease
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Chapter
Can Renal Mass Biopsy Improve Outcomes? Impact on Clinical Decision-Making
More frequent utilization of cross-sectional imaging has led to an increase in the incidental diagnosis and a subsequent rise in incidence of small renal masses. Historical biases and technical limitations hav...
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Chapter
Objectifying Complexity of Kidney Cancers: Relationship of Tumor Anatomy and Outcomes
A standardized classification system to communicate relevant attributes of renal tumors did not exist until recently. The emergence and subsequent validation of the RENAL nephrometry score and soon thereafter ...
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Article
Robotic versus laparoscopic radical nephrectomy: a large multi-institutional analysis (ROSULA Collaborative Group)
To compare the outcomes of robotic radical nephrectomy (RRN) to those of laparoscopic radical nephrectomy (LRN) for large renal masses.
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Article
A national survey of radiation oncologists and urologists on prediction tools and nomograms for localized prostate cancer
Although prediction tools for prostate cancer (PCa) are essential for high-quality treatment decision-making, little is known about the degree of confidence in existing tools and whether they are used in clini...
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Article
Prostate Cancer Patients’ Understanding of the Gleason Scoring System: Implications for Shared Decision-Making
The Gleason scoring system is a key component of a prostate cancer diagnosis, since it indicates disease aggressiveness. It also serves as a risk communication tool that facilitates shared treatment decision-m...
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Chapter
Imaging-Based Scoring Systems for the Risk Stratification of Renal Tumors
Individualizing the care of patients presenting with a renal mass requires the evaluation of a broad array of considerations including anatomic complexity of the patient’s tumor. In order to better objectify t...
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Article
Open AccessThe convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma
Renal cell carcinoma (RCC) is the most common form of kidney cancer. While cure remains exceptionally infrequent in RCC patients with systemic or recurrent disease, current targeted molecular strategies, inclu...
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Article
Focal ablation therapy for renal cancer in the era of active surveillance and minimally invasive partial nephrectomy
Partial nephrectomy remains the optimal treatment for the management of small renal masses (SRMs), but several focal ablative techniques also exist, of which r...
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Article
Open AccessLDL cholesterol counteracts the antitumour effect of tyrosine kinase inhibitors against renal cell carcinoma
Treatment with tyrosine kinase inhibitors (TKIs) significantly improves survival of patients with renal cell carcinoma (RCC). However, about one-quarter of the RCC patients are primarily refractory to treatmen...
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Article
Update on Renal Mass Biopsy
Renal masses are diagnosed with an increasing frequency. However, a significant proportion of these masses are benign, and the majority of malignant tumors are biologically indolent. Furthermore, renal tumors ...
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Article
Clinically localized type 1 and 2 papillary renal cell carcinomas have similar survival outcomes following surgery
We aimed to determine incidence, pathologic findings, prognostic factors and clinical outcomes for patients with clinically localized papillary RCC.
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Article
Key advances promise progress for kidney cancer patients
Kidney cancer research in 2014 was characterized by a diverse array of studies. Advances were made in both the localized and the metastatic renal cell carcinoma (RCC) arenas. Importantly, significant progress ...
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Article
Zinc and zinc transporters in prostate carcinogenesis
Kolenko et al. consider the evidence supporting a role for zinc in prostate carcinogenesis and discuss how a better understanding of the mechanisms of zinc homeostasis could be used to improve diagnosis and treat...
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Chapter
Objectifying Complexity of Kidney Cancers: Relationships of Tumor Anatomy and Outcomes
A standardized classification system to communicate relevant attributes of renal tumors did not exist until recently. The emergence and subsequent validation of the RENAL nephrometry score and soon thereafter ...
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Chapter
Active Surveillance of the Small Renal Mass
Increased abdominal imaging has led to the significant incidental detection of clinically localized renal tumors. While the gold standard remains surgical excision, no demonstrable improvement in cancer-specif...
