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Chapter and Conference Paper
A VR Office Applying Modern Search and Filter Concepts for Knowledge Workers
Virtual, Augmented and Mixed Reality (VAMR) fields of applications are met with the demand for innovation within the field to build the bridge between the theory of its use and our daily life. However, much of...
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Article
Open AccessQuantitative normal values of helical flow, flow jets and wall shear stress of healthy volunteers in the ascending aorta
4D flow MRI enables quantitative assessment of helical flow. We sought to generate normal values and elucidate changes of helical flow (duration, volume, length, velocities and rotational direction) and flow j...
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Article
Open AccessGlobally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone
The neoplastic stromal cells of giant cell tumor of bone (GCTB) carry a mutation in H3F3A, leading to a mutant histone variant, H3.3-G34W, as a sole recurrent genetic alteration. We show that in patient-derived s...
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Chapter
Future of Medicine: Models in Predictive Diagnostics and Personalized Medicine
Molecular medicine is undergoing fundamental changes driving the whole area towards a revolution in modern medicine. The breakthrough was generated the fast-develo** technologies in molecular biology since t...
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Chapter and Conference Paper
Rights Management with NFC Smartphones and Electronic ID Cards: A Proof of Concept for Modern Car Sharing
Numerous contactless smartcards (and the corresponding RFID readers) are compatible with NFC, e.g., Mifare cards and the governmental ID card in Germany called nPA. NFC-enabled smartphones and other NFC object...
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Article
Open AccessThe “Virtual Patient” system: modeling cancer using deep sequencing technologies for personalized cancer treatment
Cancer is a complex disease involving many different genomic and epigenomic changes, mutations, copy number changes, loss of heterozygosity etc. These differences cause tumors with the same pathological classi...
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Article
Open AccessMonte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network
Gene Regulatory Networks (GRNs) control the differentiation, specification and function of cells at the genomic level. The levels of interactions within large GRNs are of enormous depth and complexity. Details...
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Article
Geochronology of fluid-induced eclogite and amphibolite facies metamorphic reactions in a subduction–collision system, Bergen Arcs, Norway
Rb–Sr multimineral isochron data for metamorphic veins allow to date separate increments of the mineral reaction history of polymetamorphic terranes. Granulite facies rocks of the Lindås nappe, Bergen Arcs, No...
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Article
Open AccessA global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks
The genome of the sea urchin Strongylocentrotus purpuratus has recently been sequenced because it is a major model system for the study of gene regulatory networks. Embryonic expression patterns for most genes ar...
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Article
Factorial validity and norm data comparison of the Short Form 12 in patients with inflammatory-rheumatic disease
Measuring quality of life is increasingly considered as an outcome criterion in clinical studies. In order to assess quality of life, disease specific as well as generic instruments are used. Generic instrumen...
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Article
Crystallization and very rapid exhumation of the youngest Alpine eclogites (Tauern Window, Eastern Alps) from Rb/Sr mineral assemblage analysis
Multimineral Rb/Sr internal isochrons from eclogite facies rocks of the Eclogite Zone (Tauern Window, Eastern Alps) consistently yield an Early Oligocene age of 31.5±0.7 Ma. This age has been obtained both for...
