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  1. Article

    Open Access

    Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers

    Among the 10% of pancreatic cancers that occur in a familial context, around a third carry a pathogenic variant in a cancer predisposition gene. Genetic studies of pancreatic cancer predisposition are limited ...

    Sofie Joris, Philippe Giron, Catharina Olsen, Sara Seneca, Alexander Gheldof… in BMC Cancer (2024)

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  2. No Access

    Article

    Rare genetic variants potentially involved in ovarian hyperstimulation syndrome

    We aim to investigate whether there is a genetic predisposition in women who developed ovarian hyperstimulation syndrome (OHSS) after GnRH antagonist protocol with GnRH agonist trigger and freeze-all approach.

    Katrien Stouffs, Sari Daelemans… in Journal of Assisted Reproduction and Genet… (2019)

  3. Article

    Open Access

    Convert your favorite protein modeling program into a mutation predictor: “MODICT”

    Predict whether a mutation is deleterious based on the custom 3D model of a protein.

    Ibrahim Tanyalcin, Katrien Stouffs, Dorien Daneels, Carla Al Assaf… in BMC Bioinformatics (2016)

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  4. No Access

    Article

    Evolutionary functional analysis and molecular regulation of the ZEB transcription factors

    ZEB1 and ZEB2, which are members of the ZEB family of transcription factors, play a pivotal role in the development of the vertebrate embryo. However, recent evidence shows that both proteins can also drive th...

    Alexander Gheldof, Paco Hulpiau, Frans van Roy… in Cellular and Molecular Life Sciences (2012)