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Article
Open AccessIntegrated correlators at strong coupling in an orbifold of \( \mathcal{N} \) = 4 SYM
We consider the 4d N \( \mathcal{N} \) = 2 superconformal quiver gauge theo...
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Article
Open AccessMultidisciplinary follow-up in a patient with Morgagni hernia leads to diagnosis of Marfan syndrome
congenital diaphragmatic hernia (CDH) is a birth defect occurring in isolated or syndromic (chromosomal or monogenic) conditions. The diaphragmatic defect can be the most common one: left-sided posterolateral,...
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Article
Open AccessWilson loop correlators at strong coupling in \( \mathcal{N} \) = 2 quiver gauge theories
We consider 4-dimensional N \( \mathcal{N} \) = 2 superconformal quiver the...
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Article
Open AccessDefect correlators in a \( \mathcal{N} \) = 2 SCFT at strong coupling
We study the correlation function between one single-trace scalar operator and a circular Wilson loop in the 4d N ...
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Article
Open Accessβ3-adrenergic receptor on tumor-infiltrating lymphocytes sustains IFN-γ-dependent PD-L1 expression and impairs anti-tumor immunity in neuroblastoma
Neuroblastoma (NB) is a heterogeneous extracranial tumor occurring in childhood. A distinctive feature of NB tumors is their neuroendocrine ability to secrete catecholamines, which in turn, via β-adrenergic recep...
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Article
Open AccessSafety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs
The antimicrobial peptide SET-M33 is under study for the development of a new antibiotic against major Gram-negative pathogens. Here we report the toxicological evaluation of SET-M33 administered intravenously...
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Article
Infantile hemangiomas β3-adrenoceptor overexpression is associated with nonresponse to propranolol
Propranolol (antagonist of β1-/β2-AR but minimally active against β3-AR) is currently the first-line treatment for infantile hemangiomas (IH). Its efficacy is attributed to the blockade of β2-AR. However, its suc...
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Article
Open AccesseHealth for patients with rare diseases: the eHealth Working Group of the European Reference Network on Rare Multisystemic Vascular Diseases (VASCERN)
The European Reference Network on Rare Multisystemic Vascular Diseases (VASCERN) was launched in 2017 and involves, to date, 35 highly specialised multidisciplinary expert centres (from the 30 full Healthcare ...
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Article
Open AccessThe Coulomb and Higgs branches of \( \mathcal{N} \) = 1 theories of Class \( {\mathcal{S}}_k \)
Even though for generic N \( \mathcal{N} \) = 1 theories it is not possible...
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Article
Open Accessβ3-adrenoreceptor blockade reduces tumor growth and increases neuronal differentiation in neuroblastoma via SK2/S1P2 modulation
Neuroblastoma (NB) is the most frequently observed among extracranial pediatric solid tumors. It displays an extreme clinical heterogeneity, in particular for the presentation at diagnosis and response to trea...
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Article
Open AccessEuropean reference network for rare vascular diseases (VASCERN) consensus statement for the screening and management of patients with pathogenic ACTA2 variants
The ACTA2 gene encodes for smooth muscle specific α-actin, a critical component of the contractile apparatus of the vascular smooth muscle cell. Pathogenic variants in the ACTA2 gene are the most frequently encou...
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Article
Open AccessP67 Unreliable Pulse Wave Velocity Values Provided by Algorithm-Based Device: A Study in Marfan Syndrome
To evaluate the reliability of algorithm-based aortic pulse wave velocity (PWV) estimated by the Mobil-O-Graph (IEM, Germany) compared to a standard non-invasive measurement of aortic PWV (carotid-femoral PWV)...
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Article
Open Access4d \( \mathcal{N}=3 \) indices via discrete gauging
A class of 4d N = 3 ...
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Article
Open AccessNear-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging
Near-infrared quantum dots (NIR QDs) are a new class of fluorescent labels with excellent bioimaging features, such as high fluorescence intensity, good fluorescence stability, sufficient electron density, and...
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Article
Open AccessTowards deconstruction of the Type D (2,0) theory
We propose a four-dimensional supersymmetric theory that deconstructs, in a particular limit, the six-dimensional (2, 0) theory of type D k . This 4d theory is defined by a neckl...
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Article
Open AccessNon-connected gauge groups and the plethystic program
We present in the context of supersymmetric gauge theories an extension of the Weyl integration formula, first discovered by Robert Wendt [1], which applies to a class of non-connected Lie groups. This allows ...
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Article
Diagnostics of myasthenic syndromes: detection of anti-AChR and anti-MuSK antibodies
This paper presents the Italian guidelines for autoantibody testing in myasthenia gravis that have been developed following a consensus process built on questionnaire-based surveys, internet contacts and discu...
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Article
Open AccessLarge N correlation functions \( \mathcal{N} \) = 2 superconformal quivers
Using supersymmetric localization, we consider four-dimensional N ...
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Protocol
Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cell Imaging to Functional Assays and Electron Microscopy
The best approach to study the complexity of renal pathophysiology is to use living organisms. However, to limit the number of animal experiments undertaken and obtain first in humans results, in vitro models ...
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Article
Vascular smooth muscle cells in Marfan syndrome aneurysm: the broken bricks in the aortic wall
Marfan syndrome (MFS) is a connective tissue disorder with multiple organ manifestations. The genetic cause of this syndrome is the mutation of the FBN1 gene, encoding the extracellular matrix (ECM) protein fi...
