13 Result(s)
within
Alessandro Comandone
-
Article
Open AccessTreatment of bone metastases from solid tumors with bone-modifying agents: a web survey of Italian oncologists investigating patterns of practice drug prescription and prevention of side effects
Optimal use of bone-modifying agents (BMAs) in patients with bone metastases from solid tumors is uncertain in some aspects: the drug choice; the planned treatment duration and long-term therapy; the preventio...
-
Article
Prognostic role of PD-L1 and immune-related gene expression profiles in giant cell tumors of bone
Giant cell tumor of bone (GCTB) is a locally aggressive and rarely metastatic tumor, with a relatively unpredictable clinical course. A retrospective series of 46 GCTB and a control group of 24 aneurysmal bone...
-
Chapter
Soft Tissue and Bone Sarcomas
Sarcomas are a heterogeneous group of relatively rare neoplasms. The only established risk factors of soft tissue sarcomas, which represent 80% of all sarcomas, are ionizing radiation and alkylating agents use...
-
Chapter
Postoperative Surveillance in Retroperitoneal Sarcomas
-
Article
Diffusion-weighted imaging for the cellularity assessment and matrix characterization of soft tissue tumour
To evaluate whether apparent diffusion coefficient (ADC) of diffusion-weighted imaging (DWI) is able to investigate the histological features of soft tissue tumours.
-
Article
Open AccessDovitinib in patients with gastrointestinal stromal tumour refractory and/or intolerant to imatinib
This multicentre phase II trial (DOVIGIST) evaluated the antitumour activity of dovitinib as second-line treatment of patients with gastrointestinal stromal tumour (GIST) refractory to imatinib or who do not t...
-
Article
Quality of Life, Anxiety and Depression in Soft Tissue Sarcomas as Compared to More Common Tumours: An Observational Study
The aim of this study is to compare the quality of life and the levels of anxiety and depression in a relatively large group of subjects undergoing chemotherapy for soft tissue sarcoma and a control group of s...
-
Chapter
Gastrointestinal Stromal Tumors: Surgical and Medical Therapy
Gastrointestinal stromal tumors (GISTs) are rare neoplasms, with an estimated incidence of 14.2 cases/million/year in northen Italy [1]. However, they are the most common mesenchymal neoplasms of the gastroint...
-
Article
Accuracy of core-needle biopsy after contrast-enhanced ultrasound in soft-tissue tumours
Percutaneous biopsies are gaining acceptance in the diagnosis of soft-tissue tumours. Sampling in the most representative area is not easy in sarcomas of huge dimension. We hypothesised that ultrasound (US) co...
-
Article
Vinorelbine and fluorouracil plus leucovorin combination (ViFL) in patients with anthracycline and taxane-pretreated metastatic breast cancer: a phase II study
This phase II study was designed in order to evaluate efficacy and safety of the combination of vinorelbine (VNB), fluorouracil (FU) and leucovorin (LV) in patients with metastatic breast carcinoma (MBC) previ...
-
Chapter
Locoregional Therapies and Surgical Oncology
The natural history of solid neoplasms starts as a confined disease in a specific anatomical area. This period varies greatly in length and involves carcinoma in situ as well as the stage I–II of the disease. ...
-
Article
The importance of molecular biology in development, prognosis, treatment and resistance to targeted therapy in gastrointestinal stromal tumors
Gastrointestinal stromal tumors (GISTs) are the commonest mesenchymal tumors of the gastroenteric tract, and are generally believed to originate from the neoplastic transformation of the interstitial cells of ...
-
Article
Gemcitabine and vinorelbine as second-line treatment in patients with metastatic breast cancer: a phase II study
To evaluate the feasibility and activity of gemcitabine and vinorelbine as a second/third-line approach in patients with advanced breast cancer.
