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  1. Article

    Open Access

    Loss-of-function mutation in Pcsk1 increases serum APOA1 level and LCAT activity in mice

    The convertase subtilisin/kexin family 1 gene (PCSK1) has been associated in various human genetics studies with a wide spectrum of metabolic phenotypes, including early-onset obesity, hyperphagia, diabetes in...

    Aleksandra Aljakna Khan, Nakyung Kim, Ron Korstanje in Laboratory Animal Research (2022)

  2. Article

    Open Access

    Detecting early myocardial ischemia in rat heart by MALDI imaging mass spectrometry

    Diagnostics of myocardial infarction in human post-mortem hearts can be achieved only if ischemia persisted for at least 6–12 h when certain morphological changes appear in myocardium. The initial 4 h of ische...

    Aleksandra Aljakna Khan, Nasim Bararpour, Marie Gorka, Timothée Joye in Scientific Reports (2021)