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Article
Open AccessLoss-of-function mutation in Pcsk1 increases serum APOA1 level and LCAT activity in mice
The convertase subtilisin/kexin family 1 gene (PCSK1) has been associated in various human genetics studies with a wide spectrum of metabolic phenotypes, including early-onset obesity, hyperphagia, diabetes in...
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Article
Open AccessDetecting early myocardial ischemia in rat heart by MALDI imaging mass spectrometry
Diagnostics of myocardial infarction in human post-mortem hearts can be achieved only if ischemia persisted for at least 6–12 h when certain morphological changes appear in myocardium. The initial 4 h of ische...