5 Result(s)

Article

Genome-wide determinants of mortality and motor progression in Parkinson’s disease

There are 90 independent genome-wide significant genetic risk variants for Parkinson’s disease (PD) but currently only five nominated loci for PD progression. The biology of PD progression is likely to be of c...

Manuela M. X. Tan, Michael A. Lawton, Miriam I. Pollard… in npj Parkinson's Disease (2024)

Article

Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our u...

Clodagh Towns, Madeleine Richer, Simona Jasaityte… in npj Parkinson's Disease (2023)

Article

Genetic meta-analysis of levodopa induced dyskinesia in Parkinson’s disease

The genetic basis of levodopa-induced-dyskinesia (LiD) is poorly understood, and there have been few well-powered genome-wide studies. We performed a genome-wide survival meta-analyses to study the effect of g...

Alejandro Martinez-Carrasco, Raquel Real, Michael Lawton… in npj Parkinson's Disease (2023)

Article

Author Correction: The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data

Hampton L. Leonard, Ruqaya Murtadha, Alejandro Martinez-Carrasco… in npj Parkinson's Disease (2023)

Article

The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data

Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and bac...

Hampton L. Leonard, Ruqaya Murtadha, Alejandro Martinez-Carrasco… in npj Parkinson's Disease (2023)