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  1. No Access

    Article

    Maligne Rundzelltumoren

    Ewing-Sarkome stellen hochmaligne Tumoren dar, die hauptsächlich bei Kindern und Jugendlichen anzutreffen sind. Neben einer frühen klinischen Diagnostik stellt die korrekte histopathologische und molekulargene...

    Prof. Dr. Dr. Johannes Haybaeck, Albert Roessner in Der Pathologe (2020)

  2. No Access

    Article

    Knorpeltumoren: Morphologie, Genetik und Basisaspekte der Targettherapie

    Knorpeltumoren sind eine heterogene Gruppe von mesenchymalen Tumoren, deren gemeinsames Charakteristikum die Bildung von chondroblastisch differenzierter Grundsubstanz durch die Tumorzellen ist. Die Grundzüge ...

    Albert Roessner, Maria Smolle, Victor Schoeder, Johannes Haybaeck in Der Pathologe (2020)

  3. No Access

    Article

    Riesenzelltumor des Knochens

    Das histologische Bild des Riesenzelltumors des Knochens ist charakterisiert durch die zahlreichen osteoklastenähnlichen Riesenzellen. Diese sind aber nicht die eigentlichen Tumorzellen, sondern ein reaktives ...

    Albert Roessner, Maria Smolle, Johannes Haybäck in Der Pathologe (2020)

  4. No Access

    Article

    Osteoidbildende Knochentumoren

    Die wichtigsten gutartigen osteoidbildenden Tumoren sind das Osteoidosteom und das Osteoblastom. Sie wachsen langsam und sind scharf begrenzt. Histologisch zeigen die Tumorzellen keine Atypien und keine vermeh...

    Albert Roessner, Viktor Schoeder, Maria Smolle, Johannes Haybäck in Der Pathologe (2020)

  5. Article

    Open Access

    The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare - correlation with Barrett’s esophagus

    The previously reported prevalence of gastric heterotopia in the cervical esophagus, also termed inlet patch (IP), varies substantially, ranging from 0.18 to 14%. Regarding cases with adenocarcinoma within IP,...

    Ulrich Peitz, Michael Vieth, Matthias Evert, Jovana Arand… in BMC Gastroenterology (2017)

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  6. No Access

    Article

    First Delayed Resection Findings After Irreversible Electroporation (IRE) of Human Localised Renal Cell Carcinoma (RCC) in the IRENE Pilot Phase 2a Trial

    It is postulated that focal IRE affords complete ablation of soft-tissue tumours while protecting the healthy peritumoral tissue. Therefore, IRE may be an interesting option for minimally invasive, kidney-tiss...

    Johann Jakob Wendler, Jens Ricke… in CardioVascular and Interventional Radiology (2016)

  7. Article

    Open Access

    Role of tight junction proteins in gastroesophageal reflux disease

    Gastroesophageal reflux disease (GERD) is associated with impaired epithelial barrier function that is regulated by cell-cell contacts. The aim of the study was to investigate the expression pattern of selecte...

    Klaus Mönkemüller, Thomas Wex, Doerthe Kuester, Lucia C Fry… in BMC Gastroenterology (2012)

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  8. No Access

    Article

    G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer

    Recently, we have shown that the new G-protein-coupled estrogen receptor GPR30 plays an important role in the development of tamoxifen resistance in vitro. This study was undertaken to evaluate the correlation...

    Atanas Ignatov, Tanja Ignatov, Christine Weißenborn… in Breast Cancer Research and Treatment (2011)

  9. No Access

    Article

    Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells

    Tamoxifen is the most frequently used anti-hormonal drug for treatment of women with hormone-dependent breast cancer. The aim of this study is to investigate the mechanism of tamoxifen resistance and the impac...

    Atanas Ignatov, Tanja Ignatov, Albert Roessner… in Breast Cancer Research and Treatment (2010)

  10. Article

    Open Access

    Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma

    The product of CDKN2A, p16 is an essential regulator of the cell cycle controlling the entry into the S-phase. Herein, we evaluated CDKN2A promoter methylation and p16 protein expression for the differentiatio...

    Antal Csepregi, Matthias PA Ebert, Christoph Röcken, Regine Schneider-Stock… in BMC Cancer (2010)

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  11. No Access

    Article

    Allelic loss at TP53 in metastatic human endometrial carcinomas

    Loss of heterozygosity (LOH) is implicated in the initiation and progression of various human neoplasia, and is observed in both early or in advanced-stage human cancers. The current study was aimed at investi...

    Wiktor Szewczuk, Danuta Skomra, Marek Cybulski… in Clinical & Experimental Metastasis (2009)

  12. No Access

    Article

    Chronic Mucosal Inflammation of the Gastric Cardia in Gastroesophageal Reflux Disease Is Not Regulated by FOXP3-Expressing T cells

    Introduction Chronic inflammation at the cardia occurs in gastroesophageal reflux disease (GERD), as well as in the presence of Helicobacter pylori. Regulatory T cells have been demonstrated for H. pylori-induced...

    Arne Kandulski, Thomas Wex, Doerthe Kuester… in Digestive Diseases and Sciences (2009)

  13. Article

    Open Access

    APC promoter methylation and protein expression in hepatocellular carcinoma

    We investigated the impact of promoter methylation on APC protein expression in patients with hepatocellular carcinoma (HCC).

    Antal Csepregi, Christoph Röcken… in Journal of Cancer Research and Clinical On… (2008)

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  14. No Access

    Article

    P53/MDM2 overexpression in metastatic endometrial cancer: correlation with clinicopathological features and patient outcome

    Several studies have reported that p53/mdm2 distortions play a pivotal role in the development and progression of various human malignancies. However, the number of reports having evaluated simultaneously the com...

    Ryszard Jeczen, Danuta Skomra, Marek Cybulski… in Clinical & Experimental Metastasis (2007)

  15. No Access

    Article

    Localization of TFF3 peptide in human esophageal submucosal glands and gastric cardia: differentiation of two types of gastric pit cells along the rostro-caudal axis

    TFF3 (trefoil factor family 3), which is a major secretory product of the gastric antrum and the intestine, but which is nearly absent in the gastric corpus, plays a key role in the maintenance of mucosal inte...

    Irina Kouznetsova, Thomas Kalinski, Ulrich Peitz… in Cell and Tissue Research (2007)

  16. No Access

    Article

    Establishment and characterization of the permanent human cell line C3842 derived from a secondary chondrosarcoma in Ollier’s disease

    The permanent human cell line C3842 was established from a secondary chondrosarcoma in a typical case of Ollier’s disease. In the present study, we analyzed the morphological, cytogenetic and molecular biologi...

    Thomas Kalinski, Sabine Krueger, Antje-Friederike Pelz, Peter Wieacker… in Virchows Archiv (2005)

  17. No Access

    Article

    Synchronous granulomatous cholecystitis and fibroelastosis of the gallbladder

    We describe an unusual form of xanthogranulomatous cholecystitis in a 69-year-old man, with abundant intramural concrement formation and a local fibroelastosis of the adjacent interstitium and arteries. The ga...

    Matthias Evert, Albert Roessner, Christoph Röcken in Virchows Archiv (2004)

  18. No Access

    Article

    INK4a-ARF alterations in Barrett’s epithelium, intraepithelial neoplasia and Barrett’s adenocarcinoma

    The INK4a-ARF [CDKN2A]- locus on chromosome 9p21 encodes for two tumour suppressor proteins, p16INK4a and p14ARF, which act as upstream regulators of the Rb-CDK4 and p53 pathways. To study the contribution of eac...

    Michael Vieth, Regine Schneider-Stock, Knut Röhrich, Andrea May… in Virchows Archiv (2004)

  19. No Access

    Article

    A gradient of TFF3 (trefoil factor family 3) peptide synthesis within the normal human gastric mucosa

    TFF3 is a member of the trefoil factor family (TFF) peptides, which enhance the surface integrity of mucous epithelia, and is typically secreted by intestinal goblet cells together with the mucin MUC2. Reports...

    Irina Kouznetsova, Ulrich Peitz, Michael Vieth, Frank Meyer… in Cell and Tissue Research (2004)

  20. Article

    Retraction Note to: HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1038/s12020_2020_2423-x.

    Carsten Boltze, Hendrik Lehnert, Regine Schneider-Stock, Brigitte Peters… in Endocrine (2004)

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