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Article
Open AccessStructuring, reuse and analysis of electronic dental data using the Oral Health and Disease Ontology
A key challenge for improving the quality of health care is to be able to use a common framework to work with patient information acquired in any of the health and life science disciplines. Patient information...
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Article
Open AccessThe Cell Ontology 2016: enhanced content, modularization, and ontology interoperability
The Cell Ontology (CL) is an OBO Foundry candidate ontology covering the domain of canonical, natural biological cell types. Since its inception in 2005, the CL has undergone multiple rounds of revision and ex...
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Article
Open AccessOmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data
As a special class of non-coding RNAs (ncRNAs), microRNAs (miRNAs) perform important roles in numerous biological and pathological processes. The realization of miRNA functions depends largely on how miRNAs re...
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Article
Open AccessThe Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology
In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identificat...
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Article
Open AccessThe neurological disease ontology
We are develo** the Neurological Disease Ontology (ND) to provide a framework to enable representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a representati...
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Article
Open AccessThe representation of protein complexes in the Protein Ontology (PRO)
Representing species-specific proteins and protein complexes in ontologies that are both human- and machine-readable facilitates the retrieval, analysis, and interpretation of genome-scale data sets. Although ...
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Article
Open AccessModeling biomedical experimental processes with OBI
Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data e...
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Article
Open AccessAdvancing translational research with the Semantic Web
A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries in basic research to application at the clinical level. ...