11 Result(s)
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Alan R. Zinsmeister PhD
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Article
Diagnostic laparoscopy in gastroenterology
Between 1970 and 1983, we performed 1121 diagnostic laparoscopies in 1119 patients. More than 50% of the examinations were performed for malignant disease. An adequate examination was accomplished in 917 (82%)...
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Article
Meal reduces sensitivity of the stomach to pharmacologically induced dysrhythmia
The aim of this study was to determine whether food ingestion causes a change in the susceptibility of the stomach to dysrhythmia or in the characteristics of gastric dysrhythmia. The susceptibility of the sto...
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Effect of gastric dysrhythmias on postcibal motor activity of the stomach
The effect of electrical dysrhythmias on the mechanical activity of the fed stomach was investigated in 5 conscious dogs implanted with Ag-AgCl electrodes and strain gauge force transducers. Each dog was fed 1...
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Towards a less costly but accurate test of gastric emptying and small bowel transit
Our aim is to develop a less costly but accurate test of stomach emptying and small bowel transit by utilizing selected scintigraphic observations 1–6 hr after ingestion of a radiolabeled solid meal. These sel...
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Effect of viscosity on oropharyngeal and esophageal emptying in man
The effect of bolus viscosity on oropharyngeal and esophageal emptying is not known. We investigated this question in 38 healthy volunteers by measuring the transit of five semisolid boluses of varying viscosi...
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Effect of a model of canine jejunoileal orthotopic autotransplantation on jejunal and ileal transport of water and electrolytes
Canine jejunoileal transplantation induces an early profuse watery diarrhea of uncertain etiology. Our aim was to determine the temporal effects of a canine model of jejunoileal autotransplantation (a model de...
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Impact of functional dyspepsia on quality of life
Little information on functional status and well-being is available in patients with functional gastrointestinal disease. We aimed to evaluate whether quality of life is poorer in patients with functional dysp...
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Visceral perception in irritable bowel syndrome
We wished to determine if visceral perception in the rectum and stomach is altered in patients with irritable bowel syndrome and to evaluate the effects on visceral sensation of 5-HT3 receptor blockade. Twelve co...
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Nonsteroidal antiinflammatory drugs and dyspepsia in the elderly
Upper gastrointestinal tract symptoms are common in the elderly and, despite a paucity of data, nonsteroidal antiinflammatory drugs (NSAIDs) are believed to be important risk factors. We aimed to evaluate the ...
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Jejunoileal transplantation
This study was designed to determine if extrinsic innervation and intrinsic neural continuity with the duodenum (neuroenteric physiologic pathways disrupted during intestinal transplantation) modulate the char...
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A prospective psychological evaluation of patients with dysphagia of various etiologies
We hypothesized that patients who complain of dysphagia without demonstrable organic abnormality may have an underlying psychological dysfunction. We thus conducted a comprehensive assessment in three groups o...
