6 Result(s)
within
Alan F Schatzberg
Biomedicine
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Article
Genome-wide association study identifies 30 loci associated with bipolar disorder
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 v...
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Article
Open AccessStress amplifies sex differences in primate prefrontal profiles of gene expression
Stress is a recognized risk factor for mood and anxiety disorders that occur more often in women than men. Prefrontal brain regions mediate stress co**, cognitive control, and emotion. Here, we investigate s...
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Article
Open AccessPost-mortem molecular profiling of three psychiatric disorders
Psychiatric disorders are multigenic diseases with complex etiology that contribute significantly to human morbidity and mortality. Although clinically distinct, several disorders share many symptoms, suggesti...
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Article
Erratum: Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Nat. Med.; 10.1038/nm.4246; corrected online 19 December 2016 In the version of this article initially published online, the abstract contained two typos reading, “Like to other neuropsychiatric disorders,...”...
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Article
Resting-state connectivity biomarkers define neurophysiological subtypes of depression
Using functional MRI in a large multisite sample of more that 1,000 patients, four distinct neurophysiological biotypes of depression are defined. These biotypes are used to develop diagnostic classifiers that...
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Article
Slowing the progression of cognitive decline in alzheimer’s disease using mifepristone
High circulating levels of glucocorticoid hormones adversely affect cognition. Previous studies exploring the hypothalamic-pituitary-adrenal (HPA) axis and basal cortisol levels in the elderly reported that su...
