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Article
Early Postnatal Dexamethasone Diminishes Transforming Growth Factor α Localization within the Ileal Muscularis Propria of Newborn Mice and Extremely Low-birth-weight Infants
Focal small bowel perforation (FSBP) occurs most commonly in the ileum of extremely low-birth-weight (ELBW) infants. Early postnatal dexamethasone (EPD) administration results in an increased risk for FSBP in ...
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Article
Dexamethasone Administration to Newborn Mice Alters Mucosal and Muscular Morphology in the Ileum and Modulates IGF-I Localization
Glucocorticoid exposure accelerates the maturation of small bowel mucosa. We hypothesized that IGF-I, a mitogen and differentiating peptide expressed in small bowel, mediates steroid-induced change within the ...
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Article
Effects of Retinoic Acid on Airspace Development and Lung Collagen in Hyperoxia-Exposed Newborn Rats
Impaired septal formation and decreased alveolarization are often caused by hyperoxic injury to the develo** lung and are characteristic features of bronchopulmonary dysplasia. Dexamethasone, frequently admi...
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Article
Early Postnatal Dexamethasone Exposure Alters Ileum Development and Insulin-Like Growth Factor I (IGF-I) Localization in Newborn Mice
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Article
Retinoic Acid and Dexamethasone Regulate IGF Expression in Hyperoxia-Induced Lung Injury
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Article
Changes in Decorin Expression with Hyperoxic Injury to Develo** Rat Lung
Proteoglycans are extracellular matrix components that appear to play important roles in lung development and in the response to injury. Decorin, a small extracellular matrix-associated proteoglycan, is known ...
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Article
DELIVERY ROOM RESUSCITATION DECISIONS FOR EXTREMELY PREMATURE INFANTS.▴ 1557
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Article
CHANGES IN IGF EXPRESSION WITH INJURY TO DEVELOPING RAT LUNG. • 2107
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Article
Changes in IGF-I and -II, IGF Binding Protein, and IGF Receptor Transcript Abundance after Uterine Artery Ligation
ABSTRACT: Altered IGF activity may be one mechanism involved in the pathogenesis of intrauterine growth retardation (IUGR). We assessed the expression of IGF, IGF binding protein (IGFBP), and IGF receptor tran...
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Article
Tissue-Specific Developmental Regulation of the Messenger Ribonucleic Acids Encoding the Growth Hormone Receptor and the Growth Hormone Binding Protein in Rat Fetal and Postnatal Tissues
ABSTRACT: Tissue responsiveness to growth hormone is likely to be regulated by local concentrations and availability of the membrane-bound growth hormone receptor (GHR) and perhaps by the actions of the solubl...
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Article
Effects of Nursing on Growth and Development of Small Bowel Mucosa in Newborn Piglets
Trophic factors in natural milk are potential mediators of the rapid growth of intestine in neonates. To determine whether nursing stimulates growth and development of small bowel mucosa, litters of piglets we...
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Article
THE DIABETIC BB RAT - A SUITABLE MODEL OF DELAYED FETAL LUNG MATURATION
The diabetic BB rat was examined to determine its suitability as a model for the study of the effects of maternal diabetes on fetal lung development. 18 to 22 day fetuses of diabetic BB rats were evaluated for...
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Article
INCIDENCE OF HFM E POSITIVE STOOLS IN A NEONATAL INTENSIVE CARE UNIT
Since infants with necrotizing enterocolitis (NEC) often present with blood in the stools, nursery routines often dictate cessation of feedings when this sign occurs. To study the validity of this practice, we...
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Article
KIDNEY TISSUE SOMATOMEDIN-C INCREASE AFTER NEPHRECTOMY IS INDEPENDENT OF GROWTH HORMONE
Somatomedin-C (SmC) is a peptide mitogen whose serum and tissue levels are considered to be growth hormone dependent. We previously reported that tissue SmC is significantly elevated in regenerating kidneys af...
