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  1. No Access

    Article

    Comparative Evaluation of Wrinkle Treatments

    Skin wrinkles are one of the most cosmetically concerning signs of aging for women, and improvements in the visual effect of wrinkles become a matter of concern that has an impact on the quality of life. Altho...

    Masahiko Ooe, Taizo Seki, Tomoe Miura, Akiyoshi Takada in Aesthetic Plastic Surgery (2013)

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    Article

    Tretinoin Cyclodextrin Complex (RA/CyD) Causes Less Irritation with an Equal Antiwrinkle Effect Compared with Conventional Tretinoin: Clinical and Histologic Studies of Photoaged Skin

    Topical tretinoin [all-trans-retinoic acid (RA)] currently is widely used to treat photoaged skin. However, undesirable side effects such as erythema, irritation, and scaling are unavoidable and limit the use of ...

    Tomoe Miura, Akiyoshi Takada, Masahiko Ooe in Aesthetic Plastic Surgery (2012)

  3. No Access

    Article

    Improvement of pharmaceutical potential of all-trans retinoic acid with hydroxypropyl-β-cyclodextrin

    2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) includes all-trans retinoic acid (RA), covering the double-bond area of RA with substituted hydroxypropyl groups on CyD ring, as proved by the nuclear Overhauser effect (...

    Keiko Takahashi, Sayo Morimoto… in Journal of Inclusion Phenomena and Macrocy… (2011)

  4. No Access

    Article

    Options for immediate breast reconstruction following skin-sparing mastectomy

    Skin-sparing mastectomy (SSM) is a type of breast cancer surgery presupposed as breast reconstruction surgery. Cosmetically, it is an extremely effective breast cancer operation because the greater part of the...

    Kenji Yano, Ko Hosokawa, Takeshi Masuoka, Ken Matsuda, Akiyoshi Takada… in Breast Cancer (2007)