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    Article

    Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing

    The expanding applications of nonviral genomic medicines in the lung remain restricted by delivery challenges. Here, leveraging a high-throughput platform, we synthesize and screen a combinatorial library of b...

    Bowen Li, Rajith Singh Manan, Shun-Qing Liang, Akiva Gordon in Nature Biotechnology (2023)

  2. Article

    Open Access

    Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity

    There is clinical and scientific interest in develo** local anesthetics with prolonged durations of effect from single injections. The need for such is highlighted by the current opioid epidemic. Site 1 sodi...

    Chao Zhao, Andong Liu, Claudia M. Santamaria, Andre Shomorony in Nature Communications (2019)