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    Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet

    Invariant natural killer T (iNKT) cells have been suggested to play critical roles in a wide range of immune responses by acting in a proinflammatory or anti-inflammatory manner. Nonalcoholic steatohepatitis (...

    Takuya Miyagi, Tetsuo Takehara, Akio Uemura, Kumiko Nishio in Journal of Gastroenterology (2010)

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    Natural killer cell is a major producer of interferon γ that is critical for the IL-12-induced anti-tumor effect in mice

    Although the anti-tumor effect of IL-12 is mediated mostly by IFNγ, which cell types most efficiently produce IFNγ and therefore initiate or promote the anti-tumor effect of IL-12 has not been clearly determin...

    Akio Uemura, Tetsuo Takehara, Takuya Miyagi in Cancer Immunology, Immunotherapy (2010)

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    Dendritic cell-based vaccines suppress metastatic liver tumor via activation of local innate and acquired immunity

    Dendritic cell (DC)-based vaccines have been applied clinically in the setting of cancer, but tumor-associated antigens (TAAs) have not yet been enough identified in various cancers. In this study, we investig...

    Shinjiro Yamaguchi, Tomohide Tatsumi, Tetsuo Takehara in Cancer Immunology, Immunotherapy (2008)

  4. Article

    Effect of the Structural Distribution on the Mechanical Properties of Linear Low-Density Polyethylenes

    Stress strain curves and tensile impact strength were measured for fractionated specimens of the molecular weight range of 1×104–×105 (w/n=1.1–1.3) for various kinds of linear low-density polyethylene (LLDPE)...

    Satoru Hosoda, Akio Uemura in Polymer Journal (1992)

  5. Article

    Study on the Phase Separation Process of Poly(methyl methacrylate)/Poly(styrene-co-acrylonitrile) Blend by SR-SAXS

    The early stage of spinodal decomposition of partially miscible poly(methyl methacrylate)/poly(styrene-co-acrylonitrile) blend was studied by time-resolved synchrotron radiation small-angle X-ray scattering (SR-S...

    Kiyoshi Ikawa, Akio Uemura, Satoru Hosoda, Toshiro Kojima, Hideo Nomura in Polymer Journal (1991)

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    Article

    High-resolution electron microscopy of solution-grown crystals of poly (p-phenylene sulphide)

    Crystals of poly (p-phenylene sulphide) were obtained from anα-chloronaphthalene solution. The chain axis (the crystalc-axis) was usually normal to the support-film. For these crystals, high-resolution electron m...

    Akio Uemura, Masaki Tsuji, Akiyoshi Kawaguchi in Journal of Materials Science (1988)