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Article

Endosome mediated nucleocytoplasmic trafficking and endomembrane allocation is crucial to polyglutamine toxicity

Aggregation of aberrant proteins is a common pathological hallmark in neurodegeneration such as polyglutamine (polyQ) and other repeat-expansion diseases. Here through overexpression of ataxin3 C-terminal poly...

Yuyu Nan, Wenfeng Chen, Fei Chen, Lili Wei, Aiyuan Zeng… in Cell Biology and Toxicology (2024)