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235 Result(s)
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Article
The adaptation of three scleractinian corals from the perspectives of Symbiodiniaceae and photosynthesis capacity at Luhuitou fringing reef
The growth properties and environmental adaptability of different corals and symbionts vary. Therefore, insights from the adaptive mechanisms of Symbiodiniaceae in corals are very meaningful. In this study, we...
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Open AccessGenome-wide identification and integrated analysis of the FAR1/FHY3 gene family and genes expression analysis under methyl jasmonate treatment in Panax ginseng C. A. Mey.
Ginseng (Panax ginseng C. A. Mey.) is an important and valuable medicinal plant species used in traditional Chinese medicine, and its metabolite ginsenoside is the primary active ingredient. The FAR1/FHY3 gene fa...
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Article
Effects of the daily light-dark cycle on rhythms of behavior and physiology in boring giant clam Tridacna crocea
Giant clams obtain their nutrition from both filter-feeding and photosynthates produced by symbiotic zooxanthellae within their mantle tissue. The symbiotic partnerships between giant clam and zooxanthellae ar...
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Article
Open AccessLipoproteins and metabolites in diagnosing and predicting Alzheimer’s disease using machine learning
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that poses a substantial economic burden. The Random forest algorithm is effective in predicting AD; however, the key factors influencing AD ons...
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The Impact of Non-alcohol Fatty Liver Disease on Bone Mineral Density is Mediated by Sclerostin by Mendelian Randomization Study
Non-alcoholic fatty liver disease (NAFLD) has been found to be associated with osteoporosis (OP) in observational studies. However, the precise causal relationship between NAFLD and OP remains unclear. Here, w...
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Article
Open AccessAdipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer
Peritoneal metastasis, the third most common metastasis in colorectal cancer (CRC), has a poor prognosis for the rapid progression and limited therapeutic strategy. However, the molecular characteristics and p...
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Open AccessEffects of yeast culture on in vitro ruminal fermentation and microbial community of high concentrate diet in sheep
This research aimed to investigate effects of different yeast culture (YC) levels on in vitro fermentation characteristics and bacterial and fungal community under high concentrate diet. A total of 5 groups we...
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Pathogenic Aspergillus Strains Identification and Antifungal Susceptibility Analysis of 452 Cases with Otomycosis in **gzhou, China
To study the distribution of pathogenic Aspergillus strains of otomycosis in central China and the identification of their antifungal sensitivity.
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Article
The community stability of Symbiodiniaceae and bacteria of different morphological corals and linkages to coral susceptibility to anthropogenic disturbance
Variously shaped corals, such as branching and massive corals, exhibit divergent environmental susceptibility properties. The susceptibility potential of these corals may be regulated by specific symbiotic Sym...
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Article
Distributions and Trends of the Global Burden of DKD Attributable to Lead Exposure: A Systematic Analysis of GBD from 1990 to 2019
Long-term exposure to lead is associated with an increased risk of diabetic kidney disease (DKD). However, limited data exist on global trends in DKD burden attributable to lead exposure, especially across div...
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Article
Open AccessResistant starch intake facilitates weight loss in humans by resha** the gut microbiota
Emerging evidence suggests that modulation of gut microbiota by dietary fibre may offer solutions for metabolic disorders. In a randomized placebo-controlled crossover design trial (ChiCTR-TTRCC-13003333) in 3...
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Functional characterization of a catalase gene PtCat associated with sclerotia formation in Pleurotus tuber-regium
Pleurotus tuber-regium (Fr.) Sing. can evade oxygen by forming sclerotia under oxidative stress, consequently averting the development of hyperoxidative state, during which the expression level of catalase gene (
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Article
Open AccessAll-trans retinoic acid alleviates transmissible gastroenteritis virus-induced intestinal inflammation and barrier dysfunction in weaned piglets
Transmissible gastroenteritis virus (TGEV) is one of the main pathogens causing severe diarrhea of piglets. The pathogenesis of TGEV is closely related to intestinal inflammation. All-trans retinoic acid (ATRA) i...
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Article
NADPH oxidase 4-mediating oxidative stress contributes to endometriosis
NADPH oxidase 4 (NOX4) plays an important role in the regulation of oxidative stress, which is associated with endometriosis. This study aims to investigate the effects of NOX4 in endometriosis and its molecul...
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Open AccessA novel and innovative cancer classification framework through a consecutive utilization of hybrid feature selection
Cancer prediction in the early stage is a topic of major interest in medicine since it allows accurate and efficient actions for successful medical treatments of cancer. Mostly cancer datasets contain various ...
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Article
PriA is involved in Pleurotus ostreatus development and defense against Pseudomonas tolaasii
Pleurotus ostreatus is a crucial commercial mushroom widely cultivated for diverse uses. Scientists have worked on breeding disease-resistant and high-yielding varieties to secure food supply. Studies on the mole...
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Article
Maternal and newborn metabolomic changes associated with urinary polycyclic aromatic hydrocarbon metabolite concentrations at delivery: an untargeted approach
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with adverse human health outcomes. To explore the plausible associations between maternal PAH exposure and maternal/newborn met...
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Article
Open AccessDesign and evaluation of tadpole-like conformational antimicrobial peptides
Antimicrobial peptides are promising alternatives to conventional antibiotics. Herein, we report a class of “tadpole-like” peptides consisting of an amphipathic α-helical head and an aromatic tail. A structure...
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Article
Open AccessInhibition of USP7 upregulates USP22 and activates its downstream cancer-related signaling pathways in human cancer cells
Deubiquitinases (DUBs) play important roles in various human cancers and targeting DUBs is considered as a novel anticancer therapeutic strategy. Overexpression of ubiquitin specific protease 7 and 22 (USP7 an...
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Article
Populus euphratica plant cadmium resistance 2 mediates Cd tolerance by root efflux of Cd ions in poplar
Populus euphratica PePCR2 increases Cd resistance by functioning as a Cd extrusion pump and by mediating the expression of genes encoding other transporters.