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Article
Consortium of Endophytic Bacillus australimaris CK11 and Staphylococcus epidermidis CK9 from Commiphora gileadensis Mediates Tomato Resilience to Combined Salinity, Heat, and Drought Stresses
Climate change poses a critical threat to global agriculture. Plant growth-promoting bacteria (PGPB) present a sustainable approach to increase climate resilience. The study focused on isolating and screening ...
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Article
Open AccessGenetic characterization and phylogenetic analysis of the Nigella sativa (black seed) plastome
In this study, the complete plastome sequence of Nigella sativa (black seed), was analyzed for the first time. The plastome spans approximately 154,120 bp, comprising four sections: the Large Single-Copy (LSC) (8...
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Article
Open AccessStructural, dynamic behaviour, in-vitro and computational investigations of Schiff’s bases of 1,3-diphenyl urea derivatives against SARS-CoV-2 spike protein
The COVID-19 has had a significant influence on people's lives across the world. The viral genome has undergone numerous unanticipated changes that have given rise to new varieties, raising alarm on a global s...
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Article
Open AccessIdentification of small molecular inhibitors of SIRT3 by computational and biochemical approaches a potential target of breast cancer
Sirtuin 3 (SIRT3) belongs to the Sirtuin protein family, which consists of NAD+-dependent lysine deacylase, involved in the regulation of various cellular activities. Dysregulation of SIRT3 activity has been link...
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Article
Open AccessAdvancements in the biopolymer films for food packaging applications: a short review
Plastic-based films that are commonly used in the food packaging industry are tough to recycle due to their sorting issue and these films do not decay as they photodegrade into microplastics. These microplasti...
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Article
Open AccessDesign, synthesis, molecular docking study, and α-glucosidase inhibitory evaluation of novel hydrazide–hydrazone derivatives of 3,4-dihydroxyphenylacetic acid
A series of novel Schiff base derivatives (1–28) of 3,4-dihydroxyphenylacetic acid were synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high yields and their structures wer...
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Article
Polypogon monspeliensis Hepatoprotective Attributes: UHPLC/QTOF-MS/MS Metabolite Profiling and In Vitro and In Silico Studies
Polypogon monspeliensis (L.) Desf. is an annual monocot weed belonging to Poaceae family, with reported folkloric medicinal uses. In this work, the hepatoprotective potentials of the aerial parts methanolic extra...
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Article
Open AccessVerapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex Vivo Permeation, and Brain Biodistribution Studies
Verapamil hydrochloride (VRP), an antihypertensive calcium channel blocker drug has limited bioavailability and short half-life when taken orally. The present study was aimed at develo** cubosomes containing...
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Article
Correction to: Deciphering the focal role of endostatin in Alzheimer’s disease
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Synthesis and Fluorescence Properties of Imidazopyridine-Linked Coumarins via Tandem C(sp2)–H Functionalization/Decarboxylation Reaction
A catalyst-, oxidant-free and green synthetic route for direct access to a series of novel imidazopyridine-linked coumarins has been devised through tandem C(sp2)–H functionalization/decarboxylation reaction in e...
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Article
Tracking the Variations in Trace and Heavy Elements in Smoking Products Marketed in Oman and Egypt: Risk Assessment After Implementation of Constraining Protocols
Tobacco smoking is becoming one of the major worldwide concerns regarding environmental pollution as well as health threats. In 2005, the World Health Organization (WHO) released the Framework Convention On To...
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Article
Open AccessCorrection: Analysis and Interpretation of Metagenomics Data: An Approach
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Article
Attenuation of Streptozotocin-Induced Diabetic Neuropathic Allodynia by Flavone Derivative Through Modulation of GABA-ergic Mechanisms and Endogenous Biomarkers
Diabetic neuropathic pain is one of the most devasting disorders of peripheral nervous system. The loss of GABAergic inhibition is associated with the development of painful diabetic neuropathy. The current st...
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Article
Open AccessPublisher Correction: The complete plastome sequences of invasive weed Parthenium hysterophorus: genome organization, evolutionary significance, structural features, and comparative analysis
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Open AccessThe complete plastome sequences of invasive weed Parthenium hysterophorus: genome organization, evolutionary significance, structural features, and comparative analysis
Parthenium hysterophorus, a globally widespread weed, poses a significant threat to agricultural ecosystems due to its invasive nature. We investigated the chloroplast genome of P. hysterophorus in this study. Ou...
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Open AccessIdentification of new pharmacophore against SARS-CoV-2 spike protein by multi-fold computational and biochemical techniques
COVID-19 appeared as a highly contagious disease after its outbreak in December 2019 by the virus, named SARS-CoV-2. The threat, which originated in Wuhan, China, swiftly became an international emergency. Amo...
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Article
Open AccessDisseminated Basidiobolomycosis Caused by Basidiobolus omanensis in a Child with Acute Lymphoblastic Leukemia (ALL). Case Report and Literature Review
Basidiobolomycosis is an uncommon fungal infection caused by the genus Basidiobolus. In immunocompetent children, it usually causes cutaneous infection and rarely affects the gastrointestinal tract, and it is ext...
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Article
Commikuanoid D: A New Potent Carbonic Anhydrase-II Inhibitor from the Resin of Commiphora kua
A new compound, commikuanoid D, was isolated from the ethyl acetate fraction of Commiphora kua resin. The structure was unambiguously elucidated on the basis of complete spectroscopic analysis. Furthermore, the c...
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Article
Enhanced growth and stress tolerance in Barley (Hordeum vulgare) through biopriming with Aspergillus niger CSR3: a promising approach for sustainable agriculture in saline environments
Barley (Hordeum vulgare) is the fourth largest cereal crop in the world, with considerable nutritional value. Recently more studies on the toleration of barley to salt stress have been published, indicating an in...
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Article
Open AccessSynthesis of novel coumarin-based thiosemicarbazones and their implications in diabetic management via in-vitro and in-silico approaches
Diabetes mellitus has a high prevalence rate and it has been deemed a severe chronic metabolic disorder with long-term complications. This research aimed to identify compounds that could potentially inhibit th...
