19 Result(s)
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Open AccessPatent ductus arteriosus, bronchopulmonary dysplasia and pulmonary hypertension—a complex conundrum with many phenotypes?
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The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1)
To assess the impact of milrinone administration on time spent on nitric oxide (iNO) in infants with acute pulmonary hypertension (aPH). We hypothesized that intravenous milrinone used in conjunction with iNO ...
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Open AccessThe effect of patent ductus arteriosus treatment with paracetamol on pulmonary vascular resistance
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Open AccessInfants with Down syndrome and congenital heart disease have altered peri-operative immune responses
Infants with Down syndrome (DS) have an altered immune response. We aimed to characterise the inflammatory response in infants with DS and congenital heart disease (CHD) peri-operatively in comparison to infan...
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Open AccessPlatelets in pediatric and neonatal sepsis: novel mediators of the inflammatory cascade
Sepsis, a dysregulated host response to infection, has been difficult to accurately define in children. Despite a higher incidence, especially in neonates, a non-specific clinical presentation alongside a lack...
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Toward the elimination of bias in Pediatric Research
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The definition of a hemodynamically significant ductus arteriosus
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Targeted neonatal echocardiography (TNE) consult service in a large tertiary perinatal center in Canada
To describe the utilization and study the factors associated with the impact on clinical management of a new TNE consultation service in a perinatal center.
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Open AccessEducation, training, and accreditation of Neonatologist Performed Echocardiography in Europe—framework for practice
There is a growing interest worldwide in using echocardiography in the neonatal unit to act as a complement to the clinical assessment of the hemodynamic status of premature and term infants. However, there is...
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Open AccessApplication of Neonatologist Performed Echocardiography in the Assessment and Management of Neonatal Heart Failure unrelated to Congenital Heart Disease
Neonatal heart failure (HF) is a progressive disease caused by cardiovascular and non-cardiovascular abnormalities. The most common cause of neonatal HF is structural congenital heart disease, while neonatal c...
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Open AccessTissue Doppler velocity imaging and event timings in neonates: a guide to image acquisition, measurement, interpretation, and reference values
Neonatologists can use echocardiography for real-time assessment of the hemodynamic state of neonates to support clinical decision-making. There is a large body of evidence showing the shortcomings of conventi...
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Open AccessDeformation imaging and rotational mechanics in neonates: a guide to image acquisition, measurement, interpretation, and reference values
Advances in neonatal cardiac imaging permit a more comprehensive assessment of myocardial performance in neonates that could not be previously obtained with conventional imaging. Myocardial deformation analysi...
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Open AccessIntroduction to neonatologist-performed echocardiography
Cardiac ultrasound techniques are increasingly used in the neonatal intensive care unit to guide cardiorespiratory care of the sick newborn. This is the first in a series of eight review articles discussing th...
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Open AccessThe role of Neonatologist Performed Echocardiography in the assessment and management of neonatal shock
One of the major challenges of neonatal intensive care is the early detection and management of circulatory failure. Routine clinical assessment of the hemodynamic status of newborn infants is subjective and i...
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Open AccessApplication of Neonatologist Performed Echocardiography in the assessment of a patent ductus arteriosus
In many preterm infants, the ductus arteriosus remains patent beyond the first few days of life. This prolonged patency is associated with numerous adverse outcomes, but the extent to which these adverse outco...
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Open AccessApplication of Neonatologist Performed Echocardiography in the assessment and management of persistent pulmonary hypertension of the newborn
Pulmonary hypertension contributes to morbidity and mortality in both the term newborn infant, referred to as persistent pulmonary hypertension of the newborn (PPHN), and the premature infant, in the setting o...
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Noninvasive continuous cardiac output and cerebral perfusion monitoring in term infants with neonatal encephalopathy: assessment of feasibility and reliability
Noninvasive hemodynamic monitoring of infants with neonatal encephalopathy (NE) undergoing therapeutic hypothermia (TH) would be a potentially useful clinical tool. We aimed to assess the feasibility and relia...
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Open AccessRecommendations for neonatologist performed echocardiography in Europe: Consensus Statement endorsed by European Society for Paediatric Research (ESPR) and European Society for Neonatology (ESN)
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Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies
We evaluated the clinical effectiveness of variable courses of paracetamol on patent ductus arteriosus (PDA) closure and examined its effect on the in vitro term and preterm murine ductus arteriosus (DA).
