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  1. Article

    Open Access

    Brain activity associated with quadriceps strength deficits after anterior cruciate ligament reconstruction

    Prolonged treatment resistant quadriceps weakness after anterior cruciate ligament reconstruction (ACL-R) contributes to re-injury risk, poor patient outcomes, and earlier development of osteoarthritis. The or...

    Cody R. Criss, Adam S. Lepley, James A. Onate, Brian C. Clark in Scientific Reports (2023)

  2. No Access

    Article

    Combining MRI and cognitive evaluation to classify concussion in university athletes

    Current methods of concussion assessment lack the objectivity and reliability to detect neurological injury. This multi-site study uses combinations of neuroimaging (diffusion tensor imaging and resting state ...

    Monica T. Ly, Samantha E. Scarneo-Miller, Adam S. Lepley in Brain Imaging and Behavior (2022)

  3. No Access

    Article

    Protracted alterations in muscle activation strategies and knee mechanics in patients after Anterior Cruciate Ligament Reconstruction

    Altered quadriceps muscle activity can contribute to reduced ability of the muscle to quickly generate force and appropriately attenuate landing forces, exacerbating poor landing and movement strategies common...

    Julie P. Burland, Adam S. Lepley in Knee Surgery, Sports Traumatology, Arthros… (2020)

  4. No Access

    Article

    Learned Helplessness After Anterior Cruciate Ligament Reconstruction: An Altered Neurocognitive State?

    Traumatic knee injuries, such as anterior cruciate ligament (ACL) sprains, have detrimental effects on long-term health as they initiate a cycle of chronic pain, physical inactivity, and disability. Alteration...

    Julie P. Burland, Adam S. Lepley, Marc Cormier, Lindsay J. DiStefano in Sports Medicine (2019)

  5. No Access

    Article

    Quadriceps muscle function following anterior cruciate ligament reconstruction: systemic differences in neural and morphological characteristics

    Quadriceps muscle dysfunction is common following anterior cruciate ligament reconstruction (ACLR). Data considering the diversity of neural changes, in-concert with morphological adaptations of the quadriceps...

    Adam S. Lepley, Dustin R. Grooms, Julie P. Burland in Experimental Brain Research (2019)

  6. No Access

    Article

    Weak associations between body mass index and self-reported disability in people with unilateral anterior cruciate ligament reconstruction

    Individuals with an anterior cruciate ligament reconstruction (ACLR) are susceptible to persistent disability, weight gain and the development of knee osteoarthritis. It remains unclear whether body mass index...

    Brian Pietrosimone, Christopher Kuenze in Knee Surgery, Sports Traumatology, Arthros… (2018)

  7. No Access

    Article

    Central Nervous System Adaptation After Ligamentous Injury: a Summary of Theories, Evidence, and Clinical Interpretation

    The array of dysfunction occurring after ligamentous injury is tied to long-term clinical impairments in functional performance, joint stability, and health-related quality of life. To appropriately treat indi...

    Alan R. Needle, Adam S. Lepley, Dustin R. Grooms in Sports Medicine (2017)

  8. No Access

    Article

    Quadriceps corticomotor excitability following an experimental knee joint effusion

    Deficits in quadriceps strength and voluntary activation are common following knee injury. These deficits are hypothesized to generate from a neural level, however, it remains unclear how corticomotor pathways...

    Adam S. Lepley, Nael O. Bahhur in Knee Surgery, Sports Traumatology, Arthros… (2015)