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Article
Learning ratio performance on a brief visual learning and memory test moderates cognitive training gains in Double Decision task in healthy older adults
Cognitive training using a visual speed-of-processing task, called the Useful Field of View (UFOV) task, reduced dementia risk and reduced decline in activities of daily living at a 10-year follow-up in older ...
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Article
The impact of a tDCS and cognitive training intervention on task-based functional connectivity
Declines in several cognitive domains, most notably processing speed, occur in non-pathological aging. Given the exponential growth of the older adult population, declines in cognition serve as a significant p...
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Article
Frontal–temporal regional differences in brain energy metabolism and mitochondrial function using 31P MRS in older adults
Aging is a major risk for cognitive decline and transition to dementia. One well-known age-related change involves decreased brain efficiency and energy production, mediated in part by changes in mitochondrial...
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Article
Semantic processing in older adults is associated with distributed neural activation which varies by association and abstractness of words
The extent to which the neural systems underlying semantic processes degrade with advanced age remains unresolved, which motivated the current study of neural activation on functional magnetic resonance imagin...
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Article
Facilitation of working memory capacity by transcranial direct current stimulation: a secondary analysis from the augmenting cognitive training in older adults (ACT) study
Aging is a public health concern with an ever-increasing magnitude worldwide. An array of neuroscience-based approaches like transcranial direct current stimulation (tDCS) and cognitive training have garnered ...
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Article
Associations between physical exercise type, fluid intelligence, executive function, and processing speed in the oldest-old (85 +)
While much is known about the effects of physical exercise in adult humans, literature on the oldest-old (≥ 85 years old) is sparse. The present study explored the relationship between self-reported engagement...
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Article
Connecting memory and functional brain networks in older adults: a resting-state fMRI study
Limited research exists on the association between resting-state functional network connectivity in the brain and learning and memory processes in advanced age. This study examined within-network connectivity ...
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Article
Task-based functional connectivity of the Useful Field of View (UFOV) fMRI task
Declines in processing speed performance occur in aging and are a critical marker of functional independence in older adults. Numerous studies suggest that Useful Field of View (UFOV) training may ameliorate c...
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Chapter and Conference Paper
DOMINO++: Domain-Aware Loss Regularization for Deep Learning Generalizability
Out-of-distribution (OOD) generalization poses a serious challenge for modern deep learning (DL). OOD data consists of test data that is significantly different from the model’s training data. DL models that p...
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Article
Open AccessNeuroenhancement of surgeons during robotic suturing
The initial phases of robotic surgical skills acquisition are associated with poor technical performance, such as low knot-tensile strength (KTS). Transcranial direct-current stimulation (tDCS) can improve for...
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Article
Higher white matter hyperintensity load adversely affects pre-post proximal cognitive training performance in healthy older adults
Cognitive training has shown promise for improving cognition in older adults. Age-related neuroanatomical changes may affect cognitive training outcomes. White matter hyperintensities are one common brain chan...
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Article
Does transcranial direct current stimulation enhance cognitive performance in Parkinson’s disease mild cognitive impairment? An event-related potentials and neuropsychological assessment study
Parkinson’s disease-mild cognitive impairment (PD-MCI) is garnering attention as a key interventional period for cognitive impairment. Currently, there are no approved treatments for PD-MCI and encouraging res...
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Article
Cingulo-opercular and frontoparietal control network connectivity and executive functioning in older adults
Executive function is a cognitive domain that typically declines in non-pathological aging. Two cognitive control networks that are vulnerable to aging—the cingulo-opercular (CON) and fronto-parietal control (...
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Article
Proximal improvement and higher-order resting state network change after multidomain cognitive training intervention in healthy older adults
Prior randomized control trials have shown that cognitive training interventions resulted in improved proximal task performance, improved functioning of activities of daily living, and reduced dementia risk in...
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Article
A checklist for assessing the methodological quality of concurrent tES-fMRI studies (ContES checklist): a consensus study and statement
Low-intensity transcranial electrical stimulation (tES), including alternating or direct current stimulation, applies weak electrical stimulation to modulate the activity of brain circuits. Integration of tES ...
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Article
Higher-order resting state network association with the useful field of view task in older adults
Speed-of-processing abilities decline with age yet are important in performing instrumental activities of daily living. The useful field of view, or Double Decision task, assesses speed-of-processing and divid...
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Chapter and Conference Paper
DOMINO: Domain-Aware Model Calibration in Medical Image Segmentation
Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern dee...
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Article
Associations of alcohol use, HIV infection, and age with brain white matter microstructure
Heavy drinking and HIV infection are independently associated with damage to the brain’s white matter. The purpose of the current study was to investigate whether current alcohol consumption, HIV infection, an...
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Article
Reduced Working Memory is Associated with Heavier Alcohol Consumption History, Role Impairment and Executive Function Difficulties
Both HIV status and heavy alcohol use have been associated with reduced cognitive function, particularly in the domains of working memory and executive function. It is unclear what aspects of working memory an...
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Article
Is impaired dopaminergic function associated with mobility capacity in older adults?
The capacity to move is essential for independence and declines with age. Slow movement speed, in particular, is strongly associated with negative health outcomes. Prior research on mobility (herein defined as...
