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Article

A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death

Recombinant soluble TRAIL and agonistic antibodies against TRAIL receptors (DR4 and DR5) are currently being created for clinical cancer therapy, due to their selective killing of cancer cells and high safety ...

Octavian Bucur, Gabriel Gaidos, Achani Yatawara, Bodvael Pennarun… in Scientific Reports (2015)