Skip to main content

10 Result(s)

within Abed AlFatah Mansour Remove this filter

and

  1. Article

    Open Access

    Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex

    Human cortical organoids, three-dimensional neuronal cultures, are emerging as powerful tools to study brain development and dysfunction. However, whether organoids can functionally connect to a sensory networ...

    Madison N. Wilson, Martin Thunemann, **n Liu, Yichen Lu… in Nature Communications (2022)

    Download PDF (10366 KB) View Article

  2. Article

    Open Access

    Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients

    Several mutations that cause Parkinson’s disease (PD) have been identified over the past decade. These account for 15–25% of PD cases; the rest of the cases are considered sporadic. Currently, it is accepted t...

    Shani Stern, Shong Lau, Andreea Manole, Idan Rosh… in npj Parkinson's Disease (2022)

    Download PDF (5873 KB) View Article

  3. No Access

    Article

    Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

    Autism spectrum disorder (ASD) is thought to emerge during early cortical development. However, the exact developmental stages and associated molecular networks that prime disease propensity are elusive. To pr...

    Simon T. Schafer, Apua C. M. Paquola, Shani Stern, David Gosselin… in Nature Neuroscience (2019)

  4. Article

    Erratum: An in vivo model of functional and vascularized human brain organoids

    Nat. Biotechnol. 36, 432–441 (2018); published online 16 April 2018; corrected after print 18 July 2018 In the version of this article initially published, credit for part of Figure 4a was omitted. The image o...

    Abed AlFatah Mansour, J Tiago Gonçalves, Cooper W Bloyd, Hao Li… in Nature Biotechnology (2018)

    Download PDF (72 KB) View Article

  5. No Access

    Article

    An in vivo model of functional and vascularized human brain organoids

    Human cerebral organoids undergo vascularization and maturation in the mouse brain.

    Abed AlFatah Mansour, J Tiago Gonçalves, Cooper W Bloyd, Hao Li… in Nature Biotechnology (2018)

  6. Article

    Correction: Corrigendum: Derivation of novel human ground state naive pluripotent stem cells

    Nature 504, 282–286 (2013); doi:10.1038/nature12745 The reduced representation bisulphite sequencing (RRBS) data generated and analysed in this Letter were not originally uploaded to the Gene Expression Omnibu...

    Ohad Gafni, Leehee Weinberger, Abed AlFatah Mansour, Yair S. Manor, Elad Chomsky… in Nature (2015)

    Download PDF (53 KB) View Article

  7. Article

    Correction: Corrigendum: Deterministic direct reprogramming of somatic cells to pluripotency

    Nature 502, 65–70 (2013); doi:10.1038/nature12587 In this Article, the reduced representation bisulphite sequencing (RRBS) data obtained and analysed were not initially uploaded to the Gene Expression Omnibus ...

    Yoach Rais, Asaf Zviran, Shay Geula, Ohad Gafni, Elad Chomsky, Sergey Viukov… in Nature (2015)

    Download PDF (65 KB) View Article

  8. No Access

    Article

    Derivation of novel human ground state naive pluripotent stem cells

    It is known that human embryonic stem (ES) cells are more similar to mouse primed epiblast stem cells than to naive mouse ES cells; here culture conditions are determined that allow human ES and induced plurip...

    Ohad Gafni, Leehee Weinberger, Abed AlFatah Mansour, Yair S. Manor, Elad Chomsky… in Nature (2013)

  9. No Access

    Article

    Deterministic direct reprogramming of somatic cells to pluripotency

    Somatic cells can be inefficiently and stochastically reprogrammed into induced pluripotent stem (iPS) cells by exogenous expression of Oct4 (also called Pou5f1), Sox2, Klf4 and Myc (hereafter referred to as O...

    Yoach Rais, Asaf Zviran, Shay Geula, Ohad Gafni, Elad Chomsky, Sergey Viukov… in Nature (2013)

  10. No Access

    Article

    The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

    The H3K27 demethylase Utx is reported to be a critical regulator for the initiation of somatic and germ cell reprogramming.

    Abed AlFatah Mansour, Ohad Gafni, Leehee Weinberger, Asaf Zviran, Muneef Ayyash… in Nature (2012)